Endometrial cancer: molecular and therapeutic aspects

P Tsikouras, S Bouchlariotou, N Vrachnis… - European Journal of …, 2013 - Elsevier
Endometrial cancer (EC) is the most commonly diagnosed gynecologic malignancy.
Although early-stage EC is effectively treated surgically, commonly without adjuvant therapy …

[HTML][HTML] Endometrial cancer: a genetic point of view

B Bianco, CP Barbosa, CM Trevisan… - Translational Cancer …, 2020 - ncbi.nlm.nih.gov
Background Endometrial cancer is the fourth most frequent gynecological cancer and the
most frequent type of uterine cancer. There is an increase in the incidence and mortality of …

Molecular characterization of endometrial cancer and therapeutic implications

L Uppendahl, SA Mullany… - Current Opinion in …, 2017 - journals.lww.com
Molecular characterization of endometrial cancer and therape... : Current Opinion in Obstetrics
and Gynecology Molecular characterization of endometrial cancer and therapeutic implications …

New therapeutic targets for endometrial cancer: a glimpse into the preclinical sphere

I Bruchim, I Capasso, A Polonsky, S Meisel… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Endometrial cancer (EC) is the only gynecologic malignancy showing
increasing trends in incidence and mortality. While standard treatment has been effective …

Molecular bases of endometrial cancer: new roles for new actors in the diagnosis and the therapy of the disease

M Llauradó, A Ruiz, B Majem, T Ertekin, E Colás… - Molecular and cellular …, 2012 - Elsevier
Endometrial carcinoma (EC) is the most commonly diagnosed gynecologic malignancy in
the western world. The majority of these cancers are curable, but a subset about 15–20% of …

Molecular alterations in the pathogenesis of endometrial adenocarcinoma. Therapeutic implications

L Cerezo, H Cárdenes, H Michael - Clinical & Translational Oncology, 2006 - Springer
Molecular genetic evidence indicates that endometrial carcinoma likely develops as the
result of a multistep process of oncogene activation and tumor suppressor gene inactivation …

Molecular characterization of endometrial cancer and therapeutic implications

Z Chang, S Talukdar, SA Mullany… - Current opinion in …, 2019 - journals.lww.com
Molecular characterization of endometrial cancer into subgroups has prognostic and
therapeutic implications. Further development of an integrated molecular risk profile may …

Biologic markers in endometrial cancer treatment

IB Engelsen, LA Akslen, HB Salvesen - Apmis, 2009 - Wiley Online Library
With a lifetime risk among women of 2–3%, endometrial cancer is the most common pelvic
gynecologic malignancy in industrialized countries. Approximately 75% of cases are …

Endometrial carcinoma: specific targeted pathways

N Eritja, A Yeramian, BJ Chen, D Llobet-Navas… - Molecular Genetics of …, 2017 - Springer
Endometrial cancer (EC) is the most common gynecologic malignancy in the western world
with more than 280,000 cases per year worldwide. Prognosis for EC at early stages, when …

Emerging therapeutic targets in endometrial cancer

KJ Dedes, D Wetterskog, A Ashworth… - Nature reviews Clinical …, 2011 - nature.com
Endometrial cancer comprises a heterogeneous group of tumors, with distinct risk factors,
clinical presentation, histopathological features and molecular characteristics. Currently …