[HTML][HTML] Dissecting the heterogeneous cortical anatomy of autism spectrum disorder using normative models
Background The neuroanatomical basis of autism spectrum disorder (ASD) has remained
elusive, mostly owing to high biological and clinical heterogeneity among diagnosed …
elusive, mostly owing to high biological and clinical heterogeneity among diagnosed …
[HTML][HTML] A normative modelling approach reveals age-atypical cortical thickness in a subgroup of males with autism spectrum disorder
Understanding heterogeneity is an important goal on the path to precision medicine for
autism spectrum disorders (ASD). We examined how cortical thickness (CT) in ASD can be …
autism spectrum disorders (ASD). We examined how cortical thickness (CT) in ASD can be …
[HTML][HTML] Fractionating autism based on neuroanatomical normative modeling
Autism is a complex neurodevelopmental condition with substantial phenotypic, biological,
and etiologic heterogeneity. It remains a challenge to identify biomarkers to stratify autism …
and etiologic heterogeneity. It remains a challenge to identify biomarkers to stratify autism …
Mapping the heterogeneous brain structural phenotype of autism spectrum disorder using the normative model
Background Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder
characterized by substantial clinical and biological heterogeneity. Quantitative and …
characterized by substantial clinical and biological heterogeneity. Quantitative and …
Large-scale analyses of the relationship between sex, age and intelligence quotient heterogeneity and cortical morphometry in autism spectrum disorder
Significant heterogeneity across aetiologies, neurobiology and clinical phenotypes have
been observed in individuals with autism spectrum disorder (ASD). Neuroimaging-based …
been observed in individuals with autism spectrum disorder (ASD). Neuroimaging-based …
Interindividual differences in cortical thickness and their genomic underpinnings in autism spectrum disorder
C Ecker, CM Pretzsch, A Bletsch… - American Journal of …, 2022 - Am Psychiatric Assoc
Objective: Autism spectrum disorder (ASD) is accompanied by highly individualized
neuroanatomical deviations that potentially map onto distinct genotypes and clinical …
neuroanatomical deviations that potentially map onto distinct genotypes and clinical …
Multidimensional neuroanatomical subtyping of autism spectrum disorder
Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders with multiple
biological etiologies and highly variable symptoms. Using a novel analytical framework that …
biological etiologies and highly variable symptoms. Using a novel analytical framework that …
Cortical and subcortical brain morphometry differences between patients with autism spectrum disorder and healthy individuals across the lifespan: results from the …
Objective: Neuroimaging studies show structural differences in both cortical and subcortical
brain regions in children and adults with autism spectrum disorder (ASD) compared with …
brain regions in children and adults with autism spectrum disorder (ASD) compared with …
[HTML][HTML] Reconciling dimensional and categorical models of autism heterogeneity: a brain connectomics and behavioral study
Background Heterogeneity in autism spectrum disorder (ASD) has hindered the
development of biomarkers, thus motivating subtyping efforts. Most subtyping studies divide …
development of biomarkers, thus motivating subtyping efforts. Most subtyping studies divide …
Brain surface anatomy in adults with autism: the relationship between surface area, cortical thickness, and autistic symptoms
Context Neuroimaging studies of brain anatomy in autism spectrum disorder (ASD) have
mostly been based on measures of cortical volume (CV). However, CV is a product of 2 …
mostly been based on measures of cortical volume (CV). However, CV is a product of 2 …