[HTML][HTML] Global use of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes. Results from DISCOVER

SV Arnold, F Tang, A Cooper, H Chen… - BMC Endocrine …, 2022 - Springer
Background Despite strong evidence of benefit, uptake of newer glucose-lowering
medications that reduce cardiovascular risk has been low. We sought to examine global …

SGLT2 inhibitors and GLP-1 receptor agonists: established and emerging indications

E Brown, HJL Heerspink, DJ Cuthbertson, JPH Wilding - The Lancet, 2021 - thelancet.com
SGLT2 inhibitors and GLP-1 receptor agonists are used in patients with type 2 diabetes as
glucose lowering therapies, with additional benefits of weight loss and blood pressure …

Gender difference in cardiovascular outcomes with SGLT-2 inhibitors and GLP-1 receptor agonist in type 2 diabetes: a systematic review and meta-analysis of cardio …

AK Singh, R Singh - Diabetes & Metabolic Syndrome: Clinical Research & …, 2020 - Elsevier
Background and aims Type 2 diabetes confers a differential risk of cardiovascular (CV)
disease according to the gender. Whether newly approved anti-diabetic drugs like sodium …

Clinical and safety outcomes with GLP-1 receptor agonists and SGLT2 inhibitors in type 1 diabetes: a real-world study

K Edwards, X Li, I Lingvay - The Journal of Clinical …, 2023 - academic.oup.com
Context Glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose
cotransporter-2 inhibitors (SGLT2is) are used off-label in the management of type 1 diabetes …

[HTML][HTML] Major adverse cardiovascular and limb events in patients with diabetes treated with GLP-1 receptor agonists vs DPP-4 inhibitors

DSH Lin, JK Lee, WJ Chen - Diabetologia, 2021 - Springer
Aims/hypothesis The safety and efficacy of glucagon-like peptide-1 receptor agonists
(GLP1RAs) and dipeptidyl peptidase-4 inhibitors (DPP4is) in major cardiovascular adverse …

Risk of cardiovascular outcomes in patients with type 2 diabetes after addition of SGLT2 inhibitors versus sulfonylureas to baseline GLP-1RA therapy

CV Dave, SC Kim, AB Goldfine, RJ Glynn, A Tong… - Circulation, 2021 - Am Heart Assoc
Background: Several glucagon-like peptide receptor agonists (GLP-1RA) and sodium-
glucose cotransporter-2 inhibitors (SGLT2i) have demonstrated cardiovascular benefit in …

[HTML][HTML] The efficacy and safety of novel classes of glucose-lowering drugs for cardiovascular outcomes: a network meta-analysis of randomised clinical trials

DSH Lin, JK Lee, CS Hung, WJ Chen - Diabetologia, 2021 - Springer
Aims/hypothesis Several cardiovascular outcome trials on sodium–glucose cotransporter 2
inhibitors (SGLT2i) have been released recently, including trials enrolling patients with …

GLP-1 receptor agonists and heart failure in diabetes

AJ Scheen - Diabetes & metabolism, 2017 - Elsevier
The prevalence of heart failure (HF) is increasing in patients with type 2 diabetes (T2D), and
glucose-lowering agents have distinctive effects on the risk of developing HF that requires …

[HTML][HTML] GLP-1 receptor agonists in diabetic kidney disease: current evidence and future directions

JH Yu, SY Park, NH Kim, JA Seo - Kidney Research and Clinical …, 2022 - ncbi.nlm.nih.gov
With the emergence of various classes of blood glucose-lowering agents, choosing the
appropriate drug for each patient is emphasized in diabetes management. Among incretin …

[HTML][HTML] Adverse effects of GLP-1 receptor agonists

TD Filippatos, TV Panagiotopoulou… - The review of diabetic …, 2014 - ncbi.nlm.nih.gov
Abstract Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of injective anti-
diabetic drugs that improve glycemic control and many other atherosclerosis-related …