Dysregulation of inflammatory responses is considered to be a key element in autoreactive
immune responses. T regulatory cells (Tregs) are important to maintain self-tolerance and …

Abstract CD4+ CD25+ T regulatory cells (Tregs) play an essential role in maintaining
immunologic homeostasis and preventing autoimmunity. Systemic lupus erythematosus …

Autoimmune diseases are characterized by an imbalance between regulatory T cells and
effector T-cell subsets, such as Th1 and Th17 cells. Studies have confirmed that natural …

Accumulating evidence indicates an immunosuppressive role for CD4+ CD25+ regulatory T
cells (Tregs) in autoimmune diseases. Although an impaired Treg function in patients with …

T regulatory (Treg) cells have a key role in the pathogenesis of chronic inflammatory and
autoimmune diseases. A CD4+ CD69+ T cell subset has been described that behaves as …

Treg is essential to limit the extend and duration of the immune response, but its stability is
still under debate. Here we demonstrate that IL-17-producing Treg cells (Th17-like cells) …

Abstract CD4+ CD25+ Foxp3+ regulatory T cells (Treg) that specialize in the suppression of
immune responses might be critically involved in the pathogenesis of autoimmune diseases …

Regulatory T cells (Tregs) are critical mediators of immune tolerance, yet their involvement
in the autoimmune disease systemic lupus erythematosus (SLE) is incompletely understood …

FoxP3+ Treg cells are believed to play a role in the occurrence of autoimmunity and in the
determination of clinical recurrences. Contradictory reports are, however, available …

Studying the activity of homogeneous regulatory T cell (Treg) populations will advance our
understanding of their mechanisms of action and their role in human disease. Although …