Chronic wounds are a major complication of diabetes associated with high morbidity and
health care expenditures. To investigate the role of colonizing microbiota in diabetic wound …

World Health Organization considered diabetes as one of the 20th century epidemics,
estimating that over 10% of the world population is diabetic or at high risk. Self-assessment …

Wound healing is a highly coordinated and complex process, and there can be devastating
consequences if it is interrupted. It is believed that, in combination with host factors …

Nonhealing diabetic foot ulcers (DFUs) are a common and costly complication of diabetes.
Microbial burden, or “bioburden,” is believed to underlie delayed healing, although little is …

Diabetics frequently suffer from chronic, nonhealing wounds. Although bacterial colonization
and/or infection are generally acknowledged to negatively impact wound healing, the …

Diabetics chronic wounds are characterized by high levels of oxidative stress (OS) and are
often colonized by biofilm-forming bacteria that severely compromise healing and can result …

Microbial burden of chronic wounds is believed to play an important role in impaired healing
and the development of infection-related complications. However, clinical cultures have little …

Chronic nonhealing wounds have been heralded as a silent epidemic, causing significant
morbidity and mortality especially in elderly, diabetic, and obese populations. Polymicrobial …

Significance: Diabetic foot ulcers (DFU) are a major and growing public health problem.
They pose difficulties in clinical practice in both diagnosis and management. Bacterial …

Background Bacterial colonization is hypothesized to play a pathogenic role in the non-
healing state of chronic wounds. We characterized wound bacteria from a cohort of chronic …