New Cu (II) complexes with pyrazolyl derived Schiff base ligands: Synthesis and biological evaluation
Since the discovery of cisplatin there has been a continuous pursuit for new metallodrugs
showing higher efficacies and lower side effects. In this work, new copper (II) complexes (C1 …
showing higher efficacies and lower side effects. In this work, new copper (II) complexes (C1 …
DNA binding and cytotoxicity of two Cu (II) complexes containing a Schiff base ligand along with 1, 10-phenanthroline or imidazole as a coligand
We report the synthesis, characterization and biological activities of the compounds [CuL (o-
phen)](1) and [CuL (Imz)](2),(H 2 L= o-HOC 6 H 4 C (H)= NC 6 H 4 OH-o, o-phen= 1, 10 …
phen)](1) and [CuL (Imz)](2),(H 2 L= o-HOC 6 H 4 C (H)= NC 6 H 4 OH-o, o-phen= 1, 10 …
Copper (II) complexes with 4-(diethylamino) salicylaldehyde and α-diimines: Anticancer, antioxidant, antigenotoxic effects and interaction with DNA and albumins
T Vitomirov, F Dimiza, IZ Matić, T Stanojković… - Journal of Inorganic …, 2022 - Elsevier
In this article, cytotoxicity, the mechanisms of cytotoxic activity, genotoxicity, and interaction
with DNA and proteins, of two Cu (II) complexes with a salicylaldehyde derivative (4 …
with DNA and proteins, of two Cu (II) complexes with a salicylaldehyde derivative (4 …
DNA binding and cytotoxicity of some Cu (II)/Zn (II) complexes containing a carbohydrazone Schiff base ligand along with 1, 10-phenanthroline as a coligand
We report the synthesis, characterization and biological activities of the complexes [Cu (o-
phen) HL](1),[Cu (o-phen) LCu (OAc)](2), and [Zn (o-phen) LCu (OAc)](3), where, H 3 L= o …
phen) HL](1),[Cu (o-phen) LCu (OAc)](2), and [Zn (o-phen) LCu (OAc)](3), where, H 3 L= o …
Cu (II) and Co (II/III) complexes of N, O‐chelated Schiff base ligands: DNA interaction, protein binding, cytotoxicity, cell death mechanism and reactive oxygen species …
A series of copper (II)(1 and 3) and cobalt (II/III)(2, 4 and 5) complexes comprising different
imino‐phenolate ligands DCH, DTH and DBH2 (where DCH= 2, 4‐dichloro‐6 …
imino‐phenolate ligands DCH, DTH and DBH2 (where DCH= 2, 4‐dichloro‐6 …
Ternary copper (II) complexes with amino acid chains and heterocyclic bases: DNA binding, cytotoxic and cell apoptosis induction properties
T Ma, J Xu, Y Wang, H Yu, Y Yang, Y Liu… - Journal of Inorganic …, 2015 - Elsevier
Nowadays, chemotherapy is a common means of oncology. However, it is difficult to find
excellent chemotherapy drugs. Here we reported three new ternary copper (II) complexes …
excellent chemotherapy drugs. Here we reported three new ternary copper (II) complexes …
Mixed-ligand Cu (II)–vanillin Schiff base complexes; effect of coligands on their DNA binding, DNA cleavage, SOD mimetic and anticancer activity
S Tabassum, S Amir, F Arjmand, C Pettinari… - European Journal of …, 2013 - Elsevier
SOD mimics with varying coligand are momentous in developing potential
chemotherapeutic drugs. Cu (II) based SOD mimics 1–4 [CuLH (OAc)(H2O) Y)](LH= 2-((E) …
chemotherapeutic drugs. Cu (II) based SOD mimics 1–4 [CuLH (OAc)(H2O) Y)](LH= 2-((E) …
Water‐soluble Schiff base Cu(II) and Zn(II) complexes: Synthesis, DNA targeting ability and chemotherapeutic potential of Cu(II) complex for hepatocellular carcinoma – in vitro …
N Pravin, G Kumaravel… - Applied …, 2017 - Wiley Online Library
Reliable compounds with low toxicity are tempting potential chemotherapeutics. With an aim
of achieving less toxic but more potent metallodrugs, four new‐generation hydrophilic Cu (II) …
of achieving less toxic but more potent metallodrugs, four new‐generation hydrophilic Cu (II) …
Copper (II) complexes with tridentate Schiff base-like ligands: solid state and solution structures and anticancer activity
K Dankhoff, M Gold, L Kober, F Schmitt, L Pfeifer… - Dalton …, 2019 - pubs.rsc.org
We report 15 new Cu (II) complexes with tridentate NNO β-acylenamino ligands derived
from 2-picolylamine and bearing up to three alkyl, alkoxy, alkoxycarbonyl, or (pseudo) halide …
from 2-picolylamine and bearing up to three alkyl, alkoxy, alkoxycarbonyl, or (pseudo) halide …
Copper (II) complexes of coumarin-derived Schiff base ligands: Pro-or antioxidant activity in MCF-7 cells?
L MacLean, D Karcz, H Jenkins, S McClean… - Journal of inorganic …, 2019 - Elsevier
A series of copper (II) complexes of Schiff base-derived ligands (1–7) were studied for their
pro-and antioxidant behaviour in the MCF-7 human breast cancer cell line. The coordination …
pro-and antioxidant behaviour in the MCF-7 human breast cancer cell line. The coordination …