The epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2
(HER2) are the members of protein tyrosine kinase family. Their malfunction causes breast …

Abstract Epidermal Growth Factor Receptor is a multifunctional receptor and is an important
member of tyrosine kinase family. Investigation on mechanism of tumour progression and its …

Breast cancer is the most common cancer diagnosed in women and the second most
common cause of female cancer‐related deaths, with more than one million new cases …

[Frontiers in Bioscience 10, 2611-2617, September 1, 2005] 2611 EPIDERMAL GROWTH
FACTOR RECEPTOR (EGFR) TYROSINE KINASE INHIBITO Page 1 [Frontiers in Bioscience 10 …

The discovery of the molecular processes involved in cancer development has led to the
design of an array of targeted agents. These agents, directed to specific proteins in the …

An increasing number of tumors, including breast cancer, overexpress proteins of the
epidermal growth factor receptor (EGFR) family. The interaction between family members …

This review will focus on recent advances in the application of antiepidermal growth factor
receptor (anti‐EGFR) for the treatment of breast cancer. The choice of EGFR, a member of …

Human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC) accounts for
about 20% to 30% of all BC subtypes and is characterized by invasive disease and poor …

The human epidermal growth factor receptor 2 (HER2) is a member of the erbB class of
tyrosine kinase receptors. These proteins are normally expressed at the surface of healthy …

The epidermal growth factor receptor (EGFR) family contains four transmembrane tyrosine
kinases (EGFR1/ErbB1, Her2/ErbB2, Her3/ErbB3 and Her4/ErbB4) and 13 secreted …