Influence of particle size on persistence and clearance of aerosolized silver nanoparticles in the rat lung

DS Anderson, ES Patchin, RM Silva… - Toxicological …, 2015 - academic.oup.com
The growing use of silver nanoparticles (AgNPs) in consumer products raises concerns
about potential health effects. This study investigated the persistence and clearance of 2 …

Persistence of silver nanoparticles in the rat lung: Influence of dose, size, and chemical composition

DS Anderson, RM Silva, D Lee, PC Edwards… - …, 2015 - Taylor & Francis
Increasing silver nanoparticle (AgNP) use in sprays, consumer products, and medical
devices has raised concerns about potential health effects. While previous studies have …

Particle size dependent deposition and pulmonary inflammation after short-term inhalation of silver nanoparticles

HM Braakhuis, I Gosens, P Krystek, JAF Boere… - Particle and fibre …, 2014 - Springer
Background Although silver nanoparticles are currently used in more than 400 consumer
products, it is not clear to what extent they induce adverse effects after inhalation during …

Aerosolized silver nanoparticles in the rat lung and pulmonary responses over time

RM Silva, DS Anderson, J Peake… - Toxicologic …, 2016 - journals.sagepub.com
Silver nanoparticle (Ag NP) production methods are being developed and refined to
produce more uniform Ag NPs through chemical reactions involving silver salt solutions …

Mode of silver clearance following 28-day inhalation exposure to silver nanoparticles determined from lung burden assessment including post-exposure observation …

MS Jo, JK Kim, Y Kim, HP Kim, HS Kim, K Ahn… - Archives of …, 2020 - Springer
Recently revised OECD inhalation toxicity testing guidelines require measurements of lung
burden immediately after and for periods following exposure for nanomaterials. Lung burden …

Pulmonary effects of silver nanoparticle size, coating, and dose over time upon intratracheal instillation

RM Silva, DS Anderson, LM Franzi… - Toxicological …, 2015 - academic.oup.com
Abstract Silver nanoparticles (Ag NPs) can be found in myriad consumer products, medical
equipment/supplies, and public spaces. However, questions remain regarding the risks …

Silver nanoparticles in the lung: toxic effects and focal accumulation of silver in remote organs

M Wiemann, A Vennemann, F Blaske, M Sperling… - Nanomaterials, 2017 - mdpi.com
The distribution of silver (Ag) into remote organs secondary to the application of Ag
nanoparticles (Ag-NP) to the lung is still incompletely understood and was investigated in …

Difference in the toxicity mechanism between ion and nanoparticle forms of silver in the mouse lung and in macrophages

Y Arai, T Miyayama, S Hirano - Toxicology, 2015 - Elsevier
The health effects of silver nanoparticles (AgNPs) have not been well investigated, despite
AgNPs now being widely used in consumer products. We investigated the metabolic …

Quantitative biokinetics over a 28 day period of freshly generated, pristine, 20 nm silver nanoparticle aerosols in healthy adult rats after a single 1½-hour inhalation …

WG Kreyling, U Holzwarth, S Hirn, C Schleh… - Particle and Fibre …, 2020 - Springer
Background There is a steadily increasing quantity of silver nanoparticles (AgNP) produced
for numerous industrial, medicinal and private purposes, leading to an increased risk of …

A morphologic study on the fate of ultrafine silver particles: distribution pattern of phagocytized metallic silver in vitro and in vivo

S Takenaka, E Karg, W Möller, C Roth… - Inhalation …, 2000 - Taylor & Francis
The distribution pattern of inhaled particles is an important factor for the evaluation of health
effects. In this study, we morphologically investigated the fate of agglomerated ultrafine …