Synchrotron radiation offers unique properties of coherence, utilized in phase-contrast
imaging, and high flux as well as a wide energy spectrum which allow the selection of very …

Many lung disease processes are characterized by structural and functional heterogeneity
that is not directly appreciable with traditional physiological measurements. Experimental …

All lung disease dramatically alters the local motion of the lung during breathing. It stands to
reason, therefore, that detailed measurement of lung motion could provide dramatic …

Airway is a complex branching structure of many compliant tubes, and then airway geometry
and compliance have many biomechanical and clinical implications. In this study, we …

Regional changes in lung microstructure are an important component of several common
lung disorders and even in healthy lungs alveolar mechanics are poorly understood …

The interest in small animal models of human diseases has generated a need to design a
computed tomography (CT) system that operates at a microscopic level. It is particularly …

We describe the first dynamic and the first in vivo X-ray imaging studies successfully
performed at a laser-undulator-based compact synchrotron light source. The X-ray …

Volumetric data at micrometer level resolution can be acquired within a few minutes using
synchrotron-radiation-based tomographic microscopy. The field of view along the rotation …

Rationale: Cardiac contraction causes lung tissue deformation, with effects on gas flow and
mixing. Transmission of the cardiac pressure impulse through the lung parenchyma has not …

In-line free propagation phase-contrast synchrotron tomography of the lungs has been
shown to provide superior image quality compared with attenuation-based computed …