Dynamic chromatin environment of key lytic cycle regulatory regions of the Epstein-Barr virus genome
S Ramasubramanyan, K Osborn, K Flower… - Journal of …, 2012 - Am Soc Microbiol
ABSTRACT The ability of Epstein-Barr virus (EBV) to establish latency allows it to evade the
immune system and to persist for the lifetime of its host; one distinguishing characteristic is …
immune system and to persist for the lifetime of its host; one distinguishing characteristic is …
5-hydroxymethylation of the EBV genome regulates the latent to lytic switch
Latent Epstein–Barr virus (EBV) infection and cellular hypermethylation are hallmarks of
undifferentiated nasopharyngeal carcinoma (NPC). However, EBV infection of normal oral …
undifferentiated nasopharyngeal carcinoma (NPC). However, EBV infection of normal oral …
Epigenetics of Epstein Barr virus—A review
G Shareena, D Kumar - Biochimica et Biophysica Acta (BBA)-Molecular …, 2023 - Elsevier
Epstein Barr is the first-in-human oncogenic virus, closely related to numerous
lymphoproliferative and malignant diseases, including HL, BL, NPC, and GC. EBV …
lymphoproliferative and malignant diseases, including HL, BL, NPC, and GC. EBV …
Methylation of the EBV genome and establishment of restricted latency in low-passage EBV-infected 293 epithelial cells
EJ Paulson, JD Fingeroth, JL Yates, SH Speck - Virology, 2002 - Elsevier
Epstein–Barr virus (EBV) encodes multiple latency programs: a growth-transforming
program (type III) latency program and restricted-latency (types I and II) programs. During …
program (type III) latency program and restricted-latency (types I and II) programs. During …
Differential methylation of Epstein-Barr virus latency promoters facilitates viral persistence in healthy seropositive individuals
EJ Paulson, SH Speck - Journal of virology, 1999 - Am Soc Microbiol
Epstein-Barr virus (EBV) establishes a life-long infection in humans, with distinct viral latency
programs predominating during acute and chronic phases of infection. Only a subset of the …
programs predominating during acute and chronic phases of infection. Only a subset of the …
Interaction sites of the Epstein–Barr virus Zta transcription factor with the host genome in epithelial cells
A Godfrey, K Osborn, AJ Sinclair - Access Microbiology, 2021 - microbiologyresearch.org
Epstein–Barr virus (EBV) is present in a state of latency in infected memory B-cells and EBV-
associated lymphoid and epithelial cancers. Cell stimulation or differentiation of infected B …
associated lymphoid and epithelial cancers. Cell stimulation or differentiation of infected B …
Regulation of Epstein–Barr virus reactivation from latency
T Murata - Microbiology and immunology, 2014 - Wiley Online Library
Abstract The Epstein–Barr virus (EBV) is a human gamma‐herpesvirus that is implicated in
various types of proliferative diseases. Upon infection, it predominantly establishes latency …
various types of proliferative diseases. Upon infection, it predominantly establishes latency …
[HTML][HTML] Asymmetric Arginine dimethylation of Epstein–Barr virus nuclear antigen 2 promotes DNA targeting
H Gross, S Barth, RD Palermo, A Mamiani, C Hennard… - Virology, 2010 - Elsevier
The Epstein–Barr virus (EBV) growth-transforms B-lymphocytes. The virus-encoded nuclear
antigen 2 (EBNA2) is essential for transformation and activates gene expression by …
antigen 2 (EBNA2) is essential for transformation and activates gene expression by …
In vitro transcriptional activation, dimerization, and DNA-binding specificity of the Epstein-Barr virus Zta protein
PM Lieberman, AJ Berk - Journal of virology, 1990 - Am Soc Microbiol
The Epstein-Barr virus BZLF1 immediate-early gene encodes a transcriptional activator
protein, Zta, which acts as a key regulatory switch in the transition between the latent and …
protein, Zta, which acts as a key regulatory switch in the transition between the latent and …
Mapping promoter regions that are hypersensitive to methylation-mediated inhibition of transcription: application of the methylation cassette assay to the Epstein-Barr …
KD Robertson, RF Ambinder - Journal of virology, 1997 - Am Soc Microbiol
Methylation-associated transcriptional repression is recognized in many settings and may
play a role in normal differentiation and in tumorigenesis. Both sequence-specific and …
play a role in normal differentiation and in tumorigenesis. Both sequence-specific and …