Protective effects of apigenin on methylmercury-induced behavioral/neurochemical abnormalities and neurotoxicity in rats

RK Yadav, S Mehan, R Sahu, S Kumar… - Human & …, 2022 - journals.sagepub.com
Methylmercury (MeHg) is a neurotoxin that induces neurotoxicity and cell death in neurons.
MeHg increases oligodendrocyte death, glial cell activation, and motor neuron …

Protective effects of MK-801 on methylmercury-induced neuronal injury in rat cerebral cortex: involvement of oxidative stress and glutamate metabolism dysfunction

B Xu, ZF Xu, Y Deng, W Liu, HB Yang, YG Wei - Toxicology, 2012 - Elsevier
Methylmercury (MeHg) is one of the ubiquitous environmental toxicants, which can induce
oxidative stress and an indirect excitotoxicity caused by altered glutamate (Glu) metabolism …

Protective effects of memantine against methylmercury-induced glutamate dyshomeostasis and oxidative stress in rat cerebral cortex

W Liu, Z Xu, Y Deng, B Xu, Y Wei, T Yang - Neurotoxicity research, 2013 - Springer
Methylmercury (MeHg) is one of the ubiquitous environmental toxicant that leads to long-
lasting neurological deficits in animals and humans. The identification of the underlying …

[HTML][HTML] Effect of alpha-mangostin in the prevention of behavioural and neurochemical defects in methylmercury-induced neurotoxicity in experimental rats

R Sahu, S Mehan, S Kumar, A Prajapati, A Alshammari… - Toxicology reports, 2022 - Elsevier
Methylmercury (MeHg+) is a known neurotoxin that causes progressive motor neuron
degeneration in the central nervous system. Axonal degeneration, oligodendrocyte …

The protective role of tea polyphenols against methylmercury-induced neurotoxic effects in rat cerebral cortex via inhibition of oxidative stress

W Liu, Z Xu, T Yang, Y Deng, B Xu, S Feng… - Free radical …, 2014 - Taylor & Francis
Methylmercury (MeHg) is a ubiquitous environmental contaminant that could induce
oxidative stress and an indirect glutamate (Glu)-mediated excitotoxicity. However, the …

Activation of IGF-1/GLP-1 signalling via 4-hydroxyisoleucine prevents motor neuron impairments in experimental ALS-rats exposed to methylmercury-induced …

A Shandilya, S Mehan, S Kumar, P Sethi, AS Narula… - Molecules, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a severe adult motor neuron disease that causes
progressive neuromuscular atrophy, muscle wasting, weakness, and depressive-like …

Sulforaphane prevents methylmercury-induced oxidative damage and excitotoxicity through activation of the Nrf2-ARE pathway

S Feng, Z Xu, F Wang, T Yang, W Liu, Y Deng… - Molecular …, 2017 - Springer
Methylmercury (MeHg) is a prominent environmental neurotoxicant, which induces oxidative
damage and an indirect excitotoxicity caused by altered glutamate (Glu) metabolism …

Involvement of oxidative stress-mediated ERK1/2 and p38 activation regulated mitochondria-dependent apoptotic signals in methylmercury-induced neuronal cell …

TH Lu, SY Hsieh, CC Yen, HC Wu, KL Chen, DZ Hung… - Toxicology letters, 2011 - Elsevier
Methylmercury (MeHg) is well-known for causing irreversible damage in the central nervous
system as well as a risk factor for inducing neuronal degeneration. However, the molecular …

Exploring cross-talk between oxidative damage and excitotoxicity and the effects of riluzole in the rat cortex after exposure to methylmercury

Y Deng, Z Xu, B Xu, W Liu, Y Wei, Y Li, S Feng… - Neurotoxicity …, 2014 - Springer
Methylmercury (MeHg) is a ubiquitous environmental toxin that causes neurologic and
developmental diseases. Oxidative damage and excitotoxicity are putative mechanisms …

Effect of grape seed proanthocyanidin extracts on methylmercury-induced neurotoxicity in rats

H Yang, Z Xu, W Liu, Y Wei, Y Deng, B Xu - Biological trace element …, 2012 - Springer
As a highly toxic environmental pollutant, methylmercury (MeHg) can cause neurotoxicity in
animals and humans. Considering the antioxidant property of grape seed proanthocyanidin …