Skeletal muscle atrophy in individuals with advanced chronic obstructive pulmonary disease
(COPD) is associated with diminished quality of life, increased health resource use, and …

Rationale: The molecular mechanisms of muscle atrophy in chronic obstructive pulmonary
disease (COPD) are poorly understood. In wasted animals, muscle mass is regulated by …

Patients with chronic obstructive pulmonary disease (COPD) experience several systemic
manifestations such skeletal muscle dysfunction with and without muscle mass loss …

Many patients with chronic obstructive pulmonary disease (COPD) suffer from exercise
intolerance. In about 40% of the patients exercise capacity is limited by alterations in skeletal …

Muscle atrophy in chronic obstructive pulmonary disease (COPD) is associated with
reduced exercise tolerance, muscle strength, and survival. The molecular mechanisms …

Background: Chronic obstructive pulmonary disease (COPD) is a respiratory disease
associated with a systemic inflammatory response. Peripheral muscle dysfunction has been …

Background Sarcopenia was recently recognized as an independent condition by an
International Classification of Diseases, Tenth Revision, Clinical Modification code, and is a …

Peripheral muscle wasting is a feature of chronic obstructive pulmonary disease (COPD).
Potent therapeutic strategies are needed to improve peripheral muscle mass in these …

Respiratory and/or limb muscle dysfunction, which are frequently observed in chronic
obstructive pulmonary disease (COPD) patients, contribute to their disease prognosis …

Chronic obstructive pulmonary disease (COPD) will be a major leading cause of death
worldwide in the near future. Weakness and atrophy of the quadriceps are associated with a …