Duchenne muscular dystrophy (DMD) is an inherited, severe muscle wasting disease
caused by the loss of the cytoskeletal protein, dystrophin. Patients usually die in their late …

Duchenne Muscular Dystrophy (DMD) is a devastating, progressive muscle wasting disease
for which there is currently no effective treatment. DMD is caused by mutations in the …

Duchenne Muscular Dystrophy (DMD) is a fatal muscle wasting disorder caused by
dystrophin deficiency. Previous work suggested that increased expression of the dystrophin …

Duchenne muscular dystrophy is a fatal childhood disease caused by mutations that abolish
the expression of dystrophin in muscle. Utrophin is a paralogue of dystrophin and can …

The absence of dystrophin at the muscle membrane leads to Duchenne muscular dystrophy
(DMD), a severe muscle-wasting disease that is inevitably fatal in early adulthood. In …

Duchenne muscular dystrophy is an X-linked recessive muscle wasting disease caused by
the absence of the muscle cytoskeletal protein, dystrophin. Dystrophin is a member of the …

This paper reviews the evidence that utrophin, the autosomally encoded protein related to
dystrophin, may be capable of performing the same cellular functions as dystrophin. If this is …

Dystrophin-deficient mice (mdx) expressing a truncated (trc) utrophin transgene show
amelioration of the dystrophic phenotype. Here we report a multifunctional study …

Duchenne muscular dystrophy (DMD) is a progressive muscle wasting disease usually
resulting in death of patients by their early twenties1. In contrast, mice lacking dystrophin …

Duchenne muscular dystrophy (DMD) is an inherited muscle-wasting disease caused by the
absence of a muscle cytoskeletal protein, dystrophin. We have previously shown that …