The objective of the present study was to delineate the molecular mechanisms for
mitochondrial contribution to oxidative stress induced by hypoxia and reoxygenation in the …

The objective of the present study was to delineate the role of excessive accumulation of
mitochondrial nitrogen species contributing to oxidative stress induced by …

We investigated the role of nitric oxide (NO) in the mitochondrial derangement associated
with the functional response to ischemia-reperfusion of hyperthyroid rat hearts. Mitochondria …

Although the specific roles of nitric oxide (NO) in the heart in general and on cardiac
mitochondria in particular remain controversial, it is now clear that both endogenous and …

We used laser scanning confocal microscopy in combination with the nitric oxide (NO)‐
sensitive fluorescent dye DAF‐2 and the reactive oxygen species (ROS)‐sensitive dyes CM …

During cardiac ischemia–reperfusion (IR) injury, excessive generation of reactive oxygen
species (ROS) and overload of Ca2+ at the mitochondrial level both lead to opening of the …

The effects of ischemia and postischemic reperfusion on the functions of the heart and its
mitochondria were studied with special attention to the effect of nitric oxide (NO) by treatment …

Mitochondria are an important source of reactive oxygen species (ROS), implicated in
ischemia/reperfusion injury. When isolated from ischemic myocardium, mitochondria …

Mitochondrial damage is implicated in the progression of cardiac disease. Considerable
evidence suggests that proinflammatory cytokines induce oxidative stress and contribute to …

We investigated the effects of ischemia duration on the functional response of mitochondria
to reperfusion and its relationship with changes in mitochondrial susceptibility to oxidative …