Recent developments in nitric oxide donor drugs

MR Miller, IL Megson - British journal of pharmacology, 2007 - Wiley Online Library
During the 1980s, the free radical, nitric oxide (NO), was discovered to be a crucial
signalling molecule, with wide‐ranging functions in the cardiovascular, nervous and immune …

Nitric oxide donor drugs

IL Megson - Drugs Future, 2000 - access.portico.org
Research over the past 20 years has identified endogenous nitric oxide (NO) as a key
messenger molecule in the cardiovascular, nervous and immune systems. Research to date …

Nitric oxide donor drugs: an update on pathophysiology and therapeutic potential

R Scatena, P Bottoni, GE Martorana… - Expert opinion on …, 2005 - Taylor & Francis
The discovery of the multiple physiological and pathophysiological processes in which nitric
oxide (NO) is involved has promoted a great number of pharmacological researches to …

Nitric oxide donor drugs: current status and future trends

DJ Webb, IL Megson - Expert opinion on investigational drugs, 2002 - Taylor & Francis
Nitric oxide synthesised in endothelial cells that line blood vessels has a wide range of
functions that are vital for maintaining a healthy cardiovascular system. Reduced nitric oxide …

Nitric oxide as a central molecule in hypertension: Focus on the vasorelaxant activity of new nitric oxide donors

GM da Silva, MC da Silva, DVG Nascimento… - Biology, 2021 - mdpi.com
Simple Summary Nitric oxide is an important molecule that performs a variety of functions in
our bodies, especially in the cardiovascular system. In certain pathological conditions, such …

Therapeutic role of nitric oxide as emerging molecule

S Kumar, RK Singh, TR Bhardwaj - Biomedicine & Pharmacotherapy, 2017 - Elsevier
NO has many physiological roles; in inflammation, pain, rheumatoid arthritis, immune
system, gastroprotection, as antioxidant and reported to be a free radical scavenger …

Nitric-oxide releasing molecules: a new class of drugs with several major indications

JL Burgaud, JP Riffaud… - Current pharmaceutical …, 2002 - ingentaconnect.com
Nitric oxide (NO) deficiency has been implicated in many pathological and physiological
processes within the mammalian body providing a plausible biologic basis for the use of NO …

Nitric oxide: new evidence for novel therapeutic indications

SJ Wimalawansa - Expert opinion on pharmacotherapy, 2008 - Taylor & Francis
Background: Nitric oxide (NO) deficiency is implicated in many pathophysiological
processes in mammals. NO is a ubiquitous molecule involved in multiple cellular functions …

Pharmacological modulation of nitric oxide release: new pharmacological perspectives, potential benefits and risks

R Scatena, P Bottoni, A Pontoglio… - Current medicinal …, 2010 - ingentaconnect.com
Nitric oxide is becoming an increasingly important signalling molecule implicated in a
growing number of physiological and pathophysiological processes. Moreover, with the …

Nitric oxide‐releasing drugs: a novel class of effective and safe therapeutic agents

JLUC BURGAUD, E Ongini… - Annals of the New York …, 2002 - Wiley Online Library
Nitric oxide (NO) deficiency has been implicated in many pathologic processes, thus
providing a solid biological basis for the use of NO replacement therapy. Exogenous NO …