Recently, ideas about the mechanisms of glaucoma development have fundamentally
changed. The gradual accumulafion of data in the world literature indicates that the …

Background Chronic ocular hypertension (COH) models mostly focus on changes in
intraocular pressure (IOP) and loss of retinal ganglion cells (RGCs). The present study …

Abstract· AIM: To investigate the effects of transient high perfusion pressure on the retinal
vessel diameter and retinal ganglion cells.· METHODS: The animals were divided into four …

Glaucoma, the leading cause of irreversible blindness worldwide, is a neurodegenerative
disease characterized by chronic axonal damages and progressive loss of retinal ganglion …

Brimonidine, a selective α2-adrenoceptor agonist, has recently been shown to be
neuroprotective as it significantly improves survival of retinal ganglion cells (RGCs) after …

Purpose: Intraocular pressure (IOP) fluctuation is suggested as a risk factor of glaucoma.
The association between progressive degeneration of retinal ganglion cells (RGCs) and …

This study aimed to establish a novel animal model of chronic ocular hypertension (COH) by
introducing conjunctival fibroblasts (CFs) into the anterior chamber (AC) of the eyes of rats …

Purpose. We investigated retinal ganglion cell (RGC) death and activation of caspase 9 in
rats with experimental glaucoma. Methods. Elevated intraocular pressure (IOP) was induced …

Glaucoma is a neurodegenerative disease of the eye, and it presents with visual field
defects accompanied by progressive degeneration of the optic nerve and retinal ganglion …

Purpose: The aim of this study was to develop a new rabbit model of glaucoma produced by
GNPs with characteristics like human chronic glaucoma and to evaluate different …