Simple Summary The success of HPV as an infectious agent lies not within its ability to
cause disease, but rather in the adeptness of the virus to establish long-term persistent …

The papillomaviruses are small DNA viruses that encode approximately eight genes, and
require the host cell DNA replication machinery for their viral DNA replication. Thus …

Papillomaviruses infect epithelial cells, and depend on epithelial differentiation for
completion of their life cycle. The expression of viral gene products is closely regulated as …

Human papillomaviruses (HPVs) are the etiologic agents of cervical and other epithelial
cancers. Persistence of infections by high-risk HPV types is the single greatest risk factor for …

Hallmarks of HPV infection include a restricted tropism for human epithelial cells and a viral
life cycle tightly linked to the differentiation program of the host keratinocyte. This particular …

Human papillomaviruses (HPVs) are small double‐stranded DNA viruses that infect the
cutaneous and mucosal epithelium. Infection by specific HPV types has been linked to the …

Human papillomaviruses (HPV) are the etiological agents of cervical and other anogenital
malignancies. Over 100 different types of HPVs have been identified to date, and all target …

Human papillomaviruses (HPVs) have evolved over millions of years to propagate
themselves in a range of different animal species including humans. Viruses that have co …

The papillomavirus E2 proteins are pivotal to the viral life cycle and have well characterized
functions in transcriptional regulation, initiation of DNA replication and partitioning the viral …

The life cycle of human papillomaviruses (HPVs) is tightly linked to the differentiation
program of the host's stratified epithelia that it infects. E1∧ E4 is a viral protein that has been …