Papillomaviruses have evolved over many millions of years to propagate themselves at
specific epithelial niches in a range of different host species. This has led to the great …

Cervical cancer cells express high-risk human papillomavirus (HPV) E6 and E7 proteins,
and repression of HPV gene expression causes the cells to cease proliferation and undergo …

The E2 protein of human papillomavirus (HPV) binds to specific sites in the viral genome to
regulate its transcription, replication, and maintenance in infected cells. Like most regulatory …

Abstract Human Papillomaviruses (HPVs) are double-stranded DNA viruses, that infect
epithelial cells and are etiologically involved in the development of human cancer. Today …

The production of the human papillomavirus type 16 (HPV-16) is intimately tied to the
differentiation of the host epithelium that it infects. Infection occurs in the basal layer of the …

The most highly expressed protein in the productive life cycle of human papillomaviruses
(HPVs) is E1∧ E4, but its function is not well understood. To investigate the role of E1∧ E4 …

Human papillomaviruses (HPVs) cause diseases ranging from benign warts to invasive
cancers. HPVs infect epithelial cells and their replication cycle is tightly linked with the …

Human papillomaviruses (HPVs) infect keratinocytes of stratified epithelia. Long-term
persistence of infection is a critical risk factor for the development of HPV-induced …

Human papillomavirus (HPV) is a ubiquitous DNA virus that infects squamous epithelia.
Though HPV only encodes 8 genes, it is capable of causing cellular transformation and …

Human papillomaviruses (HPVs) are DNA viruses associated with major human cancers. As
such there is a strong interest in developing new means, such as vaccines and microbicides …