Bile acids are cholesterol-derived metabolites with a well-established role in the digestion
and absorption of dietary fat. More recently, the discovery of bile acids as natural ligands for …

Bile acids are derived from cholesterol to facilitate intestinal nutrient absorption and biliary
secretion of cholesterol. Recent studies have identified bile acids as signaling molecules …

Bile acid synthesis is the most significant pathway for catabolism of cholesterol and for
maintenance of whole body cholesterol homeostasis. Bile acids are physiological …

Bile acids play a critical role in the regulation of glucose, lipid, and energy metabolism
through activation of the nuclear bile acid receptor farnesoid X receptor (FXR) and …

The primary bile acids (BAs) are synthetized from cholesterol in the liver, conjugated to
glycine or taurine to increase their solubility, secreted into bile, concentrated in the …

Bile acids are generated in the liver and are traditionally recognized for their regulatory role
in multiple metabolic processes including bile acid homeostasis, nutrient absorption, and …

Besides their well-established roles in dietary lipid absorption and cholesterol homeostasis,
bile acids (BA) also act as metabolically active signaling molecules. The flux of reabsorbed …

Bile acids (BAs) are cholesterol-derived metabolites that facilitate the intestinal absorption
and transport of dietary lipids. Recently, BAs also emerged as pivotal signaling molecules …

Bile acids are increasingly recognized as key regulators of systemic metabolism. While bile
acids have long been known to play important and direct roles in nutrient absorption, bile …

Over the past decade, it has become apparent that bile acids are involved in a host of
activities beyond their classic functions in bile formation and fat absorption. The identification …