Pediatric acute myeloid leukemia (AML) is a heterogeneous disease with respect to biology
as well as outcome. In this study, we investigated whether known biological subgroups of …

Acute myeloid leukemia (AML) is a hematologic malignancy with significant molecular
heterogeneity. MicroRNAs (miRNAs) play a critical role in AML diagnosis, pathogenesis …

Acute myeloid leukemia is a hematologic malignancy with significant molecular
heterogeneity. MicroRNAs have important biological functions and play critical roles in …

The most important reason for therapy failure in pediatric acute myeloid leukemia (AML) is
relapse. In order to identify miRNAs that contribute to the clonal evolution towards relapse in …

Purpose Children with acute myeloid leukemia (AML) whose disease is refractory to
standard induction chemotherapy therapy or who experience relapse after initial response …

Background: To establish a comprehensive differential gene profile for pediatric acute
myeloid leukemia patients (pAML) based on two independent databases and verify the …

Background Recent reports have indicated that microRNAs (miRNAs) play a critical role in
malignancies, and regulations in the progress of adult leukemia. The role of miRNAs in …

Childhood acute lymphoblastic leukemia (ALL) is a genetically and prognostically
heterogeneous malignancy with a mortality rate of 20%[1]. The identification of novel …

BACKGROUND: Acute myeloid leukemia (AML) is characterized by heterogeneity in
phenotypic, genotypic, and clinical traits. miRNAs play an important role in pathogenesis …

Despite remarkable improvements in survival of childhood acute lymphoblastic leukemia
(ALL), nonresponding or relapsing patients still represent one of the most frequent causes of …