Novel therapeutic strategies are needed for paediatric patients affected by Acute Myeloid
Leukaemia (AML), particularly for those at high-risk for relapse. MicroRNAs (miRs) have …

Background: microRNAs are playing important roles in the diagnosis and prognosis of
pediatric acute lymphoblastic leukemia (ALL). Methods Expression levels of miR-100 and …

MicroRNAs (miRNAs) are short noncoding RNAs that regulate the expression of genes by
sequence-specific binding to mRNA to either promote or block its translation; they can also …

Background Acute myeloid leukemia (AML) is a highly heterogeneous disease. MicroRNAs
function as important biomarkers in the clinical prognosis of AML. Methods This study …

Our aim was to identify miRNAs that can predict risk of relapse in pediatric patients with
acute lymphoblastic leukemia (ALL). Following high‐throughput miRNA expression analysis …

Acute myeloid leukemia (AML) in children refers to a malignant tumor caused by the
abnormal proliferation of immature myeloid cells in the bone marrow and peripheral blood …

Acute myeloid leukemia (AML) has distinct subgroups characterized by different maturation
and specific chromosomal translocation. In order to gain insight into the gene expression …

Importantly, the distinct gene signatures associated with cytogenetic and molecular genetic
aberrations can also be used to accurately predict the respective leukemia subgroups. 12 …

Diagnostic biomarkers can be used to determine relapse risk in acute myeloid leukemia,
and certain genetic aberrancies have prognostic relevance. A diagnostic immunophenotypic …

Background The critical function of microRNAs in the pathogenesis and prognosis of
hematopoietic cancer has become increasingly apparent. However, only a few miRNAs …