Applications of whole cell biotransformations for the production of chiral alcohols
AWI Tan - 2006 - bonndoc.ulb.uni-bonn.de
Bioreduction of (2, 5)-hexanedione to highly enantiopure (5R)-hydroxyhexane-2-one (ee>
99%) with Lactobacillus kefiri DSM 20587 was investigated. Cell immobilisation with sodium …
99%) with Lactobacillus kefiri DSM 20587 was investigated. Cell immobilisation with sodium …
Synthesis of enantiopure (5R)-hydroxyhexane-2-one with immobilised whole cells of Lactobacillus kefiri
AWI Tan, M Fischbach, H Huebner, R Buchholz… - Applied microbiology …, 2006 - Springer
Abstract Whole-cell reduction of (2, 5)-hexanedione to yield highly enantiopure (5 R)-
hydroxyhexane-2-one (enantiomeric excess> 99%) with Lactobacillus kefiri DSM 20587 was …
hydroxyhexane-2-one (enantiomeric excess> 99%) with Lactobacillus kefiri DSM 20587 was …
Enantioselective reduction of carbonyl compounds by whole-cell biotransformation, combining a formate dehydrogenase and a (R)-specific alcohol dehydrogenase
M Ernst, B Kaup, M Müller, S Bringer-Meyer… - Applied microbiology and …, 2005 - Springer
A whole-cell biotransformation system for the reduction of prochiral carbonyl compounds,
such as methyl acetoacetate, to chiral hydroxy acid derivatives [methyl (R)-3-hydroxy …
such as methyl acetoacetate, to chiral hydroxy acid derivatives [methyl (R)-3-hydroxy …
[PDF][PDF] Ganzzellbiotransformationen mit rekombinanten Escherichia coli zur Synthese chiraler Alkohole
K Schroer - 2008 - core.ac.uk
Whole cell biotransformation processes are of special interest for the synthesis of chiral
compounds since microorganisms offer some advantages in comparison to chemical …
compounds since microorganisms offer some advantages in comparison to chemical …
Immobilized whole cells as effective catalysts for chiral alcohol production
JF Ng, S Jaenicke - Australian journal of chemistry, 2009 - CSIRO Publishing
Recombinant Escherichia coli overexpressing the gene LbADH, which encodes for an
alcohol dehydrogenase from Lactobacillus brevis, was successfully transformed and …
alcohol dehydrogenase from Lactobacillus brevis, was successfully transformed and …
Whole-cell biotransformation systems for reduction of prochiral carbonyl compounds to chiral alcohol in Escherichia coli
B Li, Y Li, D Bai, X Zhang, H Yang, J Wang, G Liu… - Scientific reports, 2014 - nature.com
Lactobacillus brevis alcohol dehydrogenase (Lb-ADH) catalyzes reduction of prochiral
carbonyl compounds to chiral alcohol and meanwhile consumes its cofactor NADH into …
carbonyl compounds to chiral alcohol and meanwhile consumes its cofactor NADH into …
[PDF][PDF] Alcohol dehydrogenases as biocatalysts for the production of enantiomerically pure chiral alcohols
J Kasprzak - 2016 - epub.ub.uni-greifswald.de
Enantiomerically pure chiral alcohols are key compounds in the production of certain
chemicals including pharmaceuticals. Chemical synthesis allows to obtain maximal yield of …
chemicals including pharmaceuticals. Chemical synthesis allows to obtain maximal yield of …
Immobilization of Acetobacter sp. CCTCC M209061 for efficient asymmetric reduction of ketones and biocatalyst recycling
XH Chen, XT Wang, WY Lou, Y Li, H Wu, MH Zong… - Microbial cell …, 2012 - Springer
Abstract Background The bacterium Acetobacter sp. CCTCC M209061 is a promising whole-
cell biocatalyst with exclusive anti-Prelog stereoselectivity for the reduction of prochiral …
cell biocatalyst with exclusive anti-Prelog stereoselectivity for the reduction of prochiral …
Biocatalytic ketone reduction—a powerful tool for the production of chiral alcohols—part II: whole-cell reductions
Enzymes are able to perform reactions under mild conditions, eg, pH and temperature, with
remarkable chemo-, regio-, and stereoselectivity. Due to this feature the number of …
remarkable chemo-, regio-, and stereoselectivity. Due to this feature the number of …
Continuous production of chiral 1, 3-butanediol using immobilized biocatalysts in a packed bed reactor: promising biocatalysis method with an asymmetric hydrogen …
N Itoh, M Nakamura, K Inoue, Y Makino - Applied microbiology and …, 2007 - Springer
An asymmetric hydrogen-transfer biocatalyst consisting of mutated Rhodococcus
phenylacetaldehyde reductase (PAR) or Leifsonia alcohol dehydrogenase (LSADH) was …
phenylacetaldehyde reductase (PAR) or Leifsonia alcohol dehydrogenase (LSADH) was …