The role of urinary metabolic profiling in systems biology research is expanding. This is
because of the use of this technology for clinical diagnostic and mechanistic studies and for …

The production of'global'metabolite profiles involves measuring low molecular-weight
metabolites (< 1 kDa) in complex biofluids/tissues to study perturbations in response to …

NMR-based metabolomics has shown considerable promise in disease diagnosis and
biomarker discovery because it allows one to nondestructively identify and quantify large …

This paper presents a simple and reliable gas chromatography/mass spectrometry (GC/MS)
method for the metabonomic analysis of human urine samples. The sample preparation …

Background Human urine gives evidence of the metabolism in the body and contains
different metabolites at various concentrations. A number of analytical techniques including …

Analysis of urine is a widely used diagnostic tool that traditionally measured one or, at most,
a few metabolites. However, the recognition of the need for a holistic approach to …

1H NMR spectroscopy potentially provides a robust approach for high-throughput metabolic
screening of biofluids such as urine and plasma, but sample handling and preparation need …

The metabolic composition of human biofluids can provide important diagnostic and
prognostic information. Among the biofluids most commonly analyzed in metabolomic …

Urine has long been a “favored” biofluid among metabolomics researchers. It is sterile, easy-
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …

Urine metabolomics has recently emerged as a prominent field for the discovery of non‐
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …