Necroptosis | New England Journal of Medicine Skip to main content The New England Journal
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Programmed cell death is a basic cellular process that is critical to maintain tissue
homeostasis. Besides apoptosis, necroptosis has more recently been discovered as another …

Necroptosis refers to a regulated form of cell death induced by a variety of stimuli. Although it
has been implicated in the pathogenesis of many diseases, there is evidence to support that …

Over the past 15 years, elegant studies have demonstrated that in certain conditions,
programed cell death resembles necrosis and depends on a unique molecular pathway with …

Programmed cell death is a key component of tissue homeostasis, normal development and
wide variety of diseases. Conventional view refers to programmed cell death form as …

Over the past few decades, mechanisms of programmed cell death have attracted the
scientific community because they are involved in diverse human diseases. Initially …

Cell death has a fundamental impact on the evolution of degenerative disorders,
autoimmune processes, inflammatory diseases, tumor formation and immune surveillance …

During the past decade, cell death researchers have witnessed a gradual but deep
conceptual revolution: it has been unequivocally shown that necrosis, which for long had …

Necroptosis is a programmed, caspase-independent cell death that is morphologically
similar to necrosis. Unlike apoptosis, necroptosis evokes inflammatory responses by …

Regulated cell death is one major factor to ensure homoeostasis in multicellular organisms.
For decades, apoptosis was considered as the sole form of regulated cell death, whereas …