Objective To characterise activation of the type I interferon (IFN) pathway in patients with
systemic lupus erythematosus (SLE), dermatomyositis (DM), polymyositis (PM), rheumatoid …

Objective Gene‐expression studies have demonstrated increased expression of interferon
(IFN)–inducible genes (IFIGs) in peripheral blood mononuclear cells (PBMCs) of many …

Objective Peripheral blood mononuclear cells (PBMCs) from patients with systemic lupus
erythematosus (SLE) have increased expression of genes typically induced by type I …

Objective The role of interferon‐α (IFNα) in the pathogenesis of systemic lupus
erythematosus (SLE) is strongly supported by gene expression studies. The aim of this study …

Objective: To study the longitudinal expression of interferon (IFN)-inducible genes in
systemic lupus erythematosus (SLE) and determine their suitability as disease biomarkers …

Objectives The relationship of immune dysregulation and autoantibody production that may
contribute to systemic lupus erythematosus (SLE) pathogenesis is unknown. This study …

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease affecting
multiple organ systems triggered by the production of autoantibodies. Previous clinical …

Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease characterized by
a large number of aberrations in the immune system, typically resulting in the formation of …

Abstract Background and aim Interferons (IFNs) are considered to be key molecules in the
pathogenesis of systemic lupus erythematosus (SLE). We measured levels of type I, II and III …

Objective To study the contribution of interferon‐α (IFNα) and IFNγ to the IFN gene
expression signature that has been observed in microarray screens of peripheral blood …