Single-step autoantibody profiling in antiphospholipid syndrome using a multi-line dot assay

K Egerer, D Roggenbuck, T Büttner, B Lehmann… - Arthritis research & …, 2011 - Springer
Introduction Diagnosis of antiphospholipid syndrome (APS) still remains a laboratory
challenge due to the great diversity of antiphospholipid antibodies (aPL) and their …

First‐Line, Non‐Criterial Antiphospholipid Antibody Testing for the Diagnosis of Antiphospholipid Syndrome in Clinical Practice: A Combination of Anti–β2 …

H Nakamura, K Oku, O Amengual… - Arthritis care & …, 2018 - Wiley Online Library
Objective To assess the value of a combination of anti–β2‐glycoprotein I (anti‐β2 GPI)
domain I antibody and anti–phosphatidylserine/prothrombin complex (anti‐PS/PT) antibody …

“Non-criteria” antiphospholipid antibodies add value to antiphospholipid syndrome diagnoses in a large Chinese cohort

T Liu, J Gu, L Wan, Q Hu, J Teng, H Liu… - Arthritis research & …, 2020 - Springer
Background Despite expansion in the 2006 Sydney antiphospholipid syndrome (APS)
classification criteria to include IgG/IgM anti-β2-glycoprotein (aβ2GPI) antibodies in addition …

Antiphospholipid antibodies detected by line immunoassay differentiate among patients with antiphospholipid syndrome, with infections and asymptomatic carriers

D Roggenbuck, MO Borghi, V Somma, T Büttner… - Arthritis research & …, 2016 - Springer
Background Antiphospholipid antibodies (aPL) can be detected in asymptomatic carriers
and infectious patients. The aim was to investigate whether a novel line immunoassay (LIA) …

[引用][C] Antiphospholipid antibody profiling: association with the clinical phenotype of antiphospholipid syndrome? Comment on the article by Otomo et al

D Roggenbuck, K Egerer, E Feist… - Arthritis & …, 2012 - Wiley Online Library
We read with great interest the article by Otomo et al, which provided a formula for improved
risk assessment in patients with APS by determining the aPL-S (1). Their addition of assays …

Clinical Characterization of Antiphospholipid Syndrome by Detection of IgG Antibodies Against β2‐Glycoprotein I Domain 1 and Domain 4/5: Ratio of Anti–Domain 1 …

L Andreoli, CB Chighizola, C Nalli… - Arthritis & …, 2015 - Wiley Online Library
Objective It has been suggested that only antibodies against domain 1 (D1) of β2‐
glycoprotein I (β2GPI) are pathogenic and diagnostic. The role of antibodies against other …

Characteristics of antiphospholipid antibody positive patients in antiphospholipid syndrome alliance for clinical trials and international networking

E Sevim, D Zisa, D Andrade, S Sciascia… - Arthritis Care & …, 2022 - discovery.ucl.ac.uk
OBJECTIVE: To describe baseline characteristics of antiphospholipid antibody (aPL)-
positive patients, overall and by clinical and laboratory subtypes, enrolled in an international …

Antiphospholipid syndrome in 2014: more clinical manifestations, novel pathogenic players and emerging biomarkers

PL Meroni, CB Chighizola, F Rovelli… - Arthritis research & …, 2014 - Springer
The clinical spectrum of the anti-phospholipid syndrome (APS) is not limited to vascular
thrombosis or miscarriages but includes additional manifestations that cannot be explained …

Characteristics of patients with antiphospholipid antibody positivity in the APS ACTION international clinical database and repository

E Sevim, D Zisa, D Andrade, S Sciascia… - Arthritis care & …, 2022 - Wiley Online Library
Objective To describe the baseline characteristics of patients with positivity for
antiphospholipid antibodies (aPLs) who were enrolled in an international registry, the …

Autoantibody profiling of patients with antiphospholipid syndrome using an automated multiplexed immunoassay system

R Tozzoli, D Villalta - Autoimmunity reviews, 2014 - Elsevier
The antiphospholipid syndrome (APS) is an autoimmune disease defined by the co-
occurrence of clinical and serological symptoms [presence of at least one of the …