Ischemic stroke (IS) is one of the most common causes of disability and death. Thrombolysis
and neuroprotection are two current major therapeutic strategies to overcome ischemic and …

Oxidative stress and a series of excessive inflammatory responses are major obstacles for
neurological functional recovery after ischemic stroke. Effective noninvasive anti …

Designing translational antioxidative agents that could scavenge free radicals produced
during reperfusion in brain ischemia stroke and alleviate neurologic damage is the main …

Rational design of nanomedicine to accelerate thrombolysis and sequentially avoid
thrombolysis-mediated reperfusion injury is still a challenge. Here, we develop a biomimetic …

Either hypoxia in an acute ischemic stroke before thrombolysis or the oxygen-boost after
thrombolysis cause a high level of free radicals, resulting in successive injuries to …

Following stroke, oxidative stress induced by reactive oxygen species (ROS) aggravates
neuronal damage and enlarges ischemic penumbra, which is devastating to stroke patients …

Acute ischemic stroke has become the major cause of mortality and disability worldwide.
Following ischemic stroke, the reperfusion injury is mainly mediated by the burst of reactive …

Ischemic stroke is a devastating disease and one of the leading causes of mortality
worldwide. Overproduction of reactive oxygen and nitrogen species (RONS) following …

Background Ischemic stroke is an acute and severe neurological disease, and reperfusion is
an effective way to reverse brain damage after stroke. However, reperfusion causes …

Zeolite-based nanomaterials have a large number of applications in the field of medicine
due to their high porosity, biocompatibility and biological stability. In this study, we designed …