We review the cellular and physiological mechanisms responsible for the regulation of blood
flow in the retina and choroid in health and disease. Due to the intrinsic light sensitivity of the …

Optimal retinal neuronal cell function requires an appropriate, tightly regulated environment,
provided by cellular barriers, which separate functional compartments, maintain their …

The retina receives its nutrients from two separate circulations: retinal and choroidal
circulation. This short overview describes the determinants in the regulation of these …

Neuronal activity in the central nervous system evokes localized changes in blood flow, a
response termed neurovascular coupling or functional hyperaemia. Modern functional …

The 2 leading causes of blindness in adults in the industrialized nations, diabetic retinopathy
and age-related macular degeneration, have been investigated thoroughly with respect to …

An overview of the functional anatomy of the retinal microcirculatory system and its
regulation mechanisms is presented. The retinal microvasculature is characterized by thin …

Evidence is accumulating that pericyte-containing microvessels, which constitute the largest
component of the circulatory system, actively regulate capillary perfusion. Because the …

The retinal vasculature supplies cells of the inner and middle layers of the retina with oxygen
and nutrients. Photic stimulation dilates retinal arterioles producing blood flow increases, a …

The aim of this study was to test the hypothesis that the neurotransmitter acetylcholine
regulates the function of pericyte-containing retinal microvessels. A vasoactive role for …

Purpose: To review control mechanisms for blood flow in the choroid, propose a system by
which venous outflow is controlled by a Starling resistor, and propose an explanation for the …