Surface modification of silica nanoparticles to reduce aggregation and nonspecific binding

RP Bagwe, LR Hilliard, W Tan - Langmuir, 2006 - ACS Publications
In this article, a systematic study of the design and development of surface-modification
schemes for silica nanoparticles is presented. The nanoparticle surface design involves an …

Fluorescent dye-doped silica nanoparticles: new tools for bioapplications

SW Bae, W Tan, JI Hong - Chemical communications, 2012 - pubs.rsc.org
The need to decipher various biological events has led to the elucidation of the molecular
mechanisms underlying a number of disease processes. Consequently, the detection and …

One-pot synthesis of surface functionalized spherical silica particles

WYD Yong, Z Zhang, G Cristobal, WS Chin - Colloids and Surfaces A …, 2014 - Elsevier
We present a general and reproducible one-pot synthesis method to prepare spherical silica
nanoparticles surface-modified with different functional groups directly from tetraethyl …

Dye-doped silica nanoparticles: synthesis, surface chemistry and bioapplications

V Gubala, G Giovannini, F Kunc, MP Monopoli… - Cancer …, 2020 - Springer
Background Fluorescent silica nanoparticles have been extensively utilised in a broad
range of biological applications and are facilitated by their predictable, well-understood …

Surface functionalization of silica nanoparticles with cysteine: a low-fouling zwitterionic surface

JE Rosen, FX Gu - Langmuir, 2011 - ACS Publications
Herein, we report on the functionalization of silica nanoparticles with a small molecule, the
amino acid cysteine, in order to create a low-fouling zwitterionic surface for nanomedicine …

Surface modification and characterization of highly dispersed silica nanoparticles by a cationic surfactant

X Ma, NH Lee, HJ Oh, JW Kim, CK Rhee… - Colloids and Surfaces A …, 2010 - Elsevier
The surface of silica nanoparticle was modified with cationic surfactant
cetyltrimethylammonium bromide (CTAB), and the different experiment conditions including …

Development of organic dye-doped silica nanoparticles for bioanalysis and biosensors

R Tapec, XJ Zhao, W Tan - Journal of nanoscience and …, 2002 - ingentaconnect.com
The combination of two silica precursors, tetraethylorthosilicate and phenyltriethoxysilane,
were utilized to synthesize organic dye-doped silica nanoparticles. The hydrophobic nature …

Optical tracking of organically modified silica nanoparticles as DNA carriers: a nonviral, nanomedicine approach for gene delivery

I Roy, TY Ohulchanskyy, DJ Bharali… - Proceedings of the …, 2005 - National Acad Sciences
This article reports a multidisciplinary approach to produce fluorescently labeled organically
modified silica nanoparticles as a nonviral vector for gene delivery and biophotonics …

Quantitative analysis and efficient surface modification of silica nanoparticles

HS Jung, DS Moon, JK Lee - Journal of Nanomaterials, 2012 - Wiley Online Library
Aminofunctional trialkoxysilanes such as aminopropyltrimethoxysilane (APTMS) and (3‐
trimethoxysilylpropyl) diethylenetriamine (DETAS) were employed as a surface modification …

Surface modification of silica nanoparticles with hydrophilic polymers

JT Park, JA Seo, SH Ahn, JH Kim, SW Kang - Journal of Industrial and …, 2010 - Elsevier
Silica (SiO2) nanoparticles grafted with a water-soluble polymer, ie nonionic poly
(oxyethylene methacrylate)(POEM) and ionic poly (styrene sulfonic acid)(PSSA) were …