Abstract Interleukin-6 (IL6) is a pleiotropic inflammatory cytokine, which is implicated in the
development and progression of several types of cancer. The-174G/C polymorphism of the …

Interleukin-6 (IL-6) is a pleiotropic cytokine that activates a classic signalling pathway upon
binding to its membrane-bound receptor (IL-6R). Alternatively, IL-6 may 'trans-signal'in a …

Background Recent studies showed that interleukin‐6 (IL‐6) played a role in tumor
development. However, available information about the prognostic significance of IL‐6 and …

Abstract Interleukin-1 (IL-1) includes a family of closely related genes; the two major
agonistic proteins, IL-1α and IL-1β, are pleiotropic and affect mainly inflammation, immunity …

Abstract Interleukin 1 (IL‐1) is a major mediator of inflammation and exerts pleiotropic effects
on many systems. To elucidate the role of its endogenous inhibitor, intracellular IL‐1 …

The interleukin‐1 (IL‐1) family consists of two major agonistic proteins, IL‐1α and IL‐1β,
which are pleiotropic and affect mainly inflammation, immunity, and hemopoiesis. The IL‐1 …

Interleukin-6 (IL-6) is a pleiotropic cytokine which plays an important role in a number of
cellular processes including proliferation, survival, differentiation, migration and invasion. IL …

Polymorphisms in interleukin-4 receptor (IL-4R) gene have been reported susceptible to a
variety of cancer types, nevertheless, data from these publications remained inconsistent …

IL‐2 receptor (IL‐2R) signalling is critical for normal lymphocyte proliferation, but its role in
cervical cancer is not fully understood. The receptor is composed of three chains: IL‐2α, IL …

Cancer growth and development is associated with the stimulation of the innate immune
system, including enhanced interleukin 2 receptor (IL-2R) expression in immune cells and …