Malaria is an endemic disease, prevalent in tropical and subtropical regions which cost half
of million deaths annually. The eradication of malaria is one of the global health priority …

Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists
in their work toward antimalarial solutions, providing practical guidance on past and current …

Human malaria infection begins with a one-time asymptomatic liver stage followed by a
cyclic symptomatic blood stage. All high-throughput malaria drug discovery efforts have …

The malaria parasite has an extraordinary ability to evade the immune system due to which
the development of a malaria vaccine is a challenging task. Extensive research on malarial …

Introduction: The development of new antimalarial drugs remains of the utmost importance,
since Plasmodium falciparum has developed resistance against nearly all …

The human malarial parasite, Plasmodium falciparum, is responsible for one of the most
infectious diseases of the world and is quickly gaining resistance to the commonly used …

Advances in research over the past few decades have greatly improved metabolomics-
based approaches in studying parasite biology and disease etiology. This improves the …

This brief review provides an overview of the pathogenesis of malaria, the human immune
response to malaria, current methodology for malaria diagnosis, and current antimalarial …

Malaria is a global health problem that causes significant mortality and morbidity annually
and a serious problem to drug therapy and discovery as current anti-malarial therapeutics …

Highlights•Eighteen FDA approved drugs identified for repurposing as antimalarials.•Drugs
classified based on safety of prescription to high-risk groups.•Identification of eleven drugs …