Nucleic acid prodrugs and methods of use thereof

GL Verdine, N Iwamoto - US Patent 9,744,183, 2017 - Google Patents
2012-09-25 First worldwide family litigation filed litigation Critical https://patents. darts-ip.
com/? family= 43429503&utm_source= google_patent&utm_medium …

Esters and malonates of SATE prodrugs

BA Mayes, AM Moussa - US Patent 9,192,621, 2015 - Google Patents
Provided herein are compounds, compositions and methods for the treatment of Flaviviridae
infections, including HCV infections. In certain embodiments, compounds and compo sitions …

4′-fluoro nucleosides for the treatment of HCV

BA Mayes, AM Moussa, AJ Stewart… - US Patent …, 2015 - Google Patents
Provided herein are compounds, compositions and methods for the treatment of Flaviviridae
infections, including HCV infections. In certain embodiments, compounds and compo sitions …

Modified 2'and 3'-nucleoside prodrugs for treating Flaviviridae infections

P LaColla, R Storer, G Gosselin… - US Patent App. 11 …, 2007 - Google Patents
(52) US Cl............ 514/7: 514/45; 514/49; 514/263.23; 514/269; 514/81: 514/86; 530/322;
544/243; 544/244; 544/276; 544/310,536/27.1: 536/28.1 (57) ABSTRACT 2" and/or …

Tricyclic-nucleoside prodrugs for treating viral infections

JD Keicher, CD Roberts - US Patent 7,534,771, 2009 - Google Patents
US7534771B2 - Tricyclic-nucleoside prodrugs for treating viral infections - Google Patents
US7534771B2 - Tricyclic-nucleoside prodrugs for treating viral infections - Google Patents …

Antiviral agents for treatment of flaviviridae infections

M Otto, K Watanabe, S Patterson… - US Patent App. 10 …, 2004 - Google Patents
US20040266723A1 - Antiviral agents for treatment of Flaviviridae infections - Google Patents
US20040266723A1 - Antiviral agents for treatment of Flaviviridae infections - Google Patents …

3′-deoxy nucleosides for the treatment of HCV

AJ Stewart, AM Moussa, BA Mayes… - US Patent …, 2016 - Google Patents
Provided herein are compounds, compositions and methods for the treatment of Flaviviridae
infections, including HCV infections. In certain embodiments, compounds and compo sitions …

2′-branched nucleosides and Flaviviridae mutation

JP Sommadossi, P LaColla, DN Standring… - US Patent …, 2014 - Google Patents
The present invention discloses a method for the treatment of Flaviviridae infection that
includes the administration of a 2'-branched nucleoside, or a pharmaceutically acceptable …

Methods for treating lentivirus infections

W Greene, K Stopak, C Denoronha - US Patent App. 11/671,951, 2007 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
34068095&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

5′-substituted nucleoside analogs and methods of use thereof for the treatment of viral diseases

VA Verma, A Arasappan, FG Njoroge… - US Patent …, 2016 - Google Patents
2014-05-15 Assigned to MERCK SHARP & DOHME CORP. reassignment MERCK SHARP
& DOHME CORP. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …