Abstract The Rome IV Committee introduced a major change in the classification of
functional gastrointestinal disorders, proposing a more restrictive definition of …

Introduction: Gastroesophageal reflux disease (GERD) is one of the most prevalent
conditions in Western Countries, normally presenting with heartburn and regurgitation. Extra …

Nonerosive reflux disease (NERD) is a common condition and the most frequent phenotype
of gastroesophageal reflux disease (GERD). NERD is extremely heterogeneous and …

Gastroesophagel reflux disease (GERD) is a common condition encountered in clinical
practice. Over the years there has been a continuous interaction between the understanding …

With widespread treatment of Helicobacter pylori infection, and that peptic ulcer diseases
are no longer considered a chronic illness and are declining in most parts of the world …

Gastro-esophageal reflux disease (GERD) occurs in about 25% of the general population.
The complexity of the disease and the multiplicity of its clinical manifestations impair the …

INTRODUCTION: Functional heartburn is defined by Rome III criteria as an endoscopy-
negative condition with normal oesophageal acid exposure time, negative symptom …

Objective To validate Lyon Consensus criteria for diagnosing gastro-oesophageal reflux
disease (GORD) by reflux monitoring. Design Manual review of impedance-pH tracings from …

Multichannel impedance pH monitoring has shown that weakly acidic refluxes are able to
generate heartburn. However, data on the role of different pH values, ranging between 4 …

Gastroduodenal reflux may cause symptoms such as chronic cough, asthma, or laryngitis.
However, we are currently limited in our diagnostic ability to identify the subgroup of patients …