BACKGROUND/AIMS: Administration of carbon tetrachloride determines liver injury,
inflammation and oxidative stress, but the molecular mechanisms of damage are only …

Objective Monocyte chemoattractant protein-1 (MCP-1, CCL2), the primary ligand for
chemokine receptor C–C chemokine receptor 2 (CCR2), is increased in livers of patients …

Considerable evidence suggests that monocytes/macrophages play a crucial role in the
process of liver injury and repair. Recent investigations have focused on the function of …

Background Increased expression of monocyte chemotactic protein-1 (MCP-1) has been
indicated as a mechanism underlying leukocyte recruitment after liver injury. In this study we …

Kupffer cells are involved in the pathogenesis of chemically mediated liver injury through
release of biologically active mediators that promote the pathogenic process. The purpose of …

Abstract Monocyte chemoattractant protein-1 (MCP-1) has been implicated in the process of
hepatic inflammation, recruiting monocytes and lymphocytes during liver injury. MCP-1 also …

Carbon tetrachloride (CCl4)-induced acute hepatitis is assumed to involve two phases. The
initial phase, initiated within 2 h after CCl4 administration, involves the generation of reactive …

Background and Aims: Monocyte chemotactic protein-1 (MCP-1) is a potent chemoattractant
for monocytes. It is involved in pathogenesis of several inflammatory diseases. Hepatic MCP …

Monocyte chemoattractant protein-1 is one of the major CC chemokines that has been
implicated in liver injury. The CC chemokine receptor, CCR2, has been identified as the …

The importance of chemokines in alcoholic liver injury has been implicated. The role of the
chemokine, monocyte chemoattractant protein‐1 (MCP‐1), elevated in patients with …