Dendritic cells (DCs) and macrophages (Mϕs) share close developmental pathways and
functional features, leading to blurring of the boundaries between these two cell lineages …

Developmental origins of dendritic cells (DCs) including conventional DCs (cDCs,
comprising cDC1 and cDC2 subsets) and plasmacytoid DCs (pDCs) remain unclear. We …

Conventional dendritic cells (cDC) are antigen-presenting cells comprising cDC1 and cDC2,
responsible for priming naive CD8+ and CD4+ T cells, respectively. Recent studies have …

To specifically tailor immune responses to a given pathogenic threat, dendritic cells (DC) are
highly heterogeneous and comprise many specialized subtypes, including conventional DC …

Dendritic cells (DCs) are critical for pathogen recognition and Ag processing/presentation.
Human monocyte-derived DCs (moDCs) have been extensively used in experimental …

Dendritic cells (DCs) possess the ability to integrate information about their environment and
communicate it to other leukocytes, shaping adaptive and innate immunity. Over the years, a …

Conventional dendritic cells (cDCs) are professional antigen-presenting cells that control the
adaptive immune response. Their subsets and developmental origins have been intensively …

Dendritic cells (DCs) are antigen-presenting cells controlling T cell activation. In humans, the
diversity, ontogeny, and functional capabilities of DC subsets are not fully understood. Here …

Highlights•cDCs, pDCs and monocytes arise from distinct developmental intermediates.•
Lineage affiliation by ontogeny provides a robust means of cell classification.•Transcriptional …

Dendritic cells (DCs) are a heterogeneous group of mononuclear phagocytes with versatile
roles in immunity. They are classified predominantly based on phenotypic and functional …