Are we restoring thyroid hormone signaling in levothyroxine-treated patients with residual symptoms of hypothyroidism?

S Casula, MD Ettleson, AC Bianco - Endocrine Practice, 2023 - Elsevier
Introduction Levothyroxine (LT4) at doses that maintain the serum thyroid-stimulating
hormone levels within the normal range constitutes the standard of care for the treatment of …

The enigma of persistent symptoms in hypothyroid patients treated with levothyroxine: A narrative review

P Perros, C Van Der Feltz‐Cornelis… - Clinical …, 2023 - Wiley Online Library
A significant minority of patients with hypothyroidism report persistent symptoms despite
achieving normal thyroid biochemistry after levothyroxine (L‐T4) replacement. Four principal …

Thyroxine treatment in patients with symptoms of hypothyroidism but thyroid function tests within the reference range: randomised double blind placebo controlled …

MA Pollock, A Sturrock, K Marshall, KM Davidson… - Bmj, 2001 - bmj.com
Objectives: To determine whether thyroxine treatment is effective in patients with symptoms
of hypothyroidism but with thyroid function tests within the reference range, and to …

[HTML][HTML] Use of thyroid hormones in hypothyroid and euthyroid patients: A 2020 THESIS questionnaire survey of members of the Danish Endocrine Society

KR Riis, JS Frølich, L Hegedüs, R Negro… - Journal of …, 2021 - Springer
Purpose The standard treatment of hypothyroidism is levothyroxine (LT4), which is available
as tablets or soft-gel capsules in Denmark. This study aimed to investigate Danish …

Use of thyroid hormones in hypothyroid and euthyroid patients: a 2020 THESIS questionnaire survey of members of the Hellenic Endocrine Society.

SA Paschou, M Alevizaki, R Attanasio, L Hegedüs… - Hormones, 2022 - Springer
Purpose To investigate current practices of specialists in the use of thyroid hormone
preparations in Greece as part of an ongoing international survey, namely THESIS …

Association of thyroid hormone therapy with quality of life and thyroid-related symptoms in patients with subclinical hypothyroidism: a systematic review and meta …

M Feller, M Snel, E Moutzouri, DC Bauer… - Jama, 2018 - jamanetwork.com
Importance The benefit of thyroid hormone therapy for subclinical hypothyroidism is
uncertain. New evidence from recent large randomized clinical trials warrants an update of …

Factors contributing to high levothyroxine doses in primary hypothyroidism: an interventional audit of a large community database

HMA Robertson, AKP Narayanaswamy, O Pereira… - Thyroid, 2014 - liebertpub.com
Background: While few hypothyroid patients require more than the expected weight-related
dose of levothyroxine, the underlying causes of larger-than-expected dosing requirements …

Health-related quality of life in patients with thyroid disorders

GP Bianchi, V Zaccheroni, E Solaroli, F Vescini… - Quality of Life …, 2004 - Springer
Limited reports are available on quality of life (HRQL) in thyroid diseases, and no data are
available in euthyroid disorders, such as goiter and Hashimoto thyroiditis. Also …

An Italian survey of compliance with major guidelines for L-thyroxine of primary hypothyroidism

S Vezzani, E Giannetta, B Altieri, A Barbonetti… - Endocrine Practice, 2018 - Elsevier
Objective: The adherence by endocrinologists to guideline regarding levothyroxine (LT4)
therapy and the compliance of patients may impact the management of hypothyroidism. The …

[PDF][PDF] Use of thyroid hormones in hypothyroid and euthyroid patients: a THESIS* questionnaire survey of Bulgarian physicians

AMI Borissova, MA Boyanov, R Attanasio… - …, 2020 - researchgate.net
Aim: to describe the use of thyroid hormones in hypothyroid and euthyroid patients by
Bulgarian physicians with a focus on the formulations of levothyroxine (LT4). Materials and …