Introduction: Amyotrophic lateral sclerosis (ALS) is a devastating illness of unclear etiology
affecting motor neurons. It causes unremitting muscle paralysis, atrophy and death usually …

Amyotrophic lateral sclerosis is a progressive neurodegenerative disease characterised by
the selective death of motor neurons. The mechanisms and processes responsible for the …

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder
involving loss of upper and lower motor neurons, with most cases ending in death within 3–5 …

Biomedical researchers interested in amyotrophic lateral sclerosis (ALS) must invoke newly
developing technologies if we are to discover pharmaceutical treatments that will help a …

Amyotrophic lateral sclerosis (ALS) is an unrelenting progressive neurodegenerative
disease causing progressive weakness, ultimately leading to death. Despite aggressive …

Introduction To date, riluzole and edaravone are the only two drugs that have successfully
passed clinical trials for the treatment of Amyotrophic Lateral Sclerosis (ALS). Unfortunately …

Several mechanisms have been proposed to account for the progressive motor neurone
death evident in amyotrophic lateral sclerosis. These include oxidative stress, neurofilament …

Introduction: Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative
disease that results in increasing disability and that is uniformly fatal. Since its approval in …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that results in
progressive loss of bulbar and limb function. Patients typically die from respiratory failure …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that affects the first
and second motoneurons (MNs), associated with muscle weakness, paralysis and finally …