[引用][C] Amyotrophic lateral sclerosis

B Murray - 2014 - Elsevier

Evaluation of the application of the European guidelines for the diagnosis and clinical care of amyotrophic lateral sclerosis (ALS) patients in six French ALS centres

B Marin, E Beghi, C Vial, E Bernard… - European journal of …, 2016 - Wiley Online Library
Background and purpose Our objective was to evaluate the extent to which the 2005
recommendations of the European Federation of Neurological Sciences (EFNS) on the …

Amyotrophic lateral sclerosis (motor neuron disease): proposed mechanisms and pathways to treatment

EF Goodall, KE Morrison - Expert reviews in molecular medicine, 2006 - cambridge.org
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterised by
loss of motor neurons. The cause of disease is unknown other than in the rare cases of …

Therapeutic targets in amyotrophic lateral sclerosis: focus on ion channels and skeletal muscle

N Tarantino, I Canfora, GM Camerino, S Pierno - Cells, 2022 - mdpi.com
Amyotrophic Lateral Sclerosis is a neurodegenerative disease caused by progressive loss
of motor neurons, which severely compromises skeletal muscle function. Evidence shows …

[PDF][PDF] Amyotrophic lateral sclerosis: from disease mechanisms to therapies

LI Bruijn - Biotechniques, 2024 - Taylor & Francis
Amyotrophic lateral sclerosis (ALS) or Lou Gehrig's disease is the most common motor
neuron disease in human adults, described as early as 1869 by a French neurobiologist and …

[PDF][PDF] Practice advisory on the treatment of amyotrophic lateral sclerosis with riluzole: Report of the Quality Standards Subcommittee of the American Academy of …

Quality Standards Subcommittee of the American … - Neurology, 1997 - AAN Enterprises
with bulbar onset, 35% of placebo-treated patients were still alive compared with 73% of
riluzoletreated patients; whereas for the limb-onset patients, 64% of placebo-treated patients …

Dose-ranging study of riluzole in amyotrophic lateral sclerosis

RS Group II, L Lacomblez, G Bensimon, V Meininger… - The Lancet, 1996 - Elsevier
BackgroundAmyotrophic lateral sclerosis (ALS) is a progressive disease with no effective
treatment. In an initial study, riluzole decreased mortality and slowed muscle-strength …

Diagnostic investigation and multidisciplinary management in motor neuron disease

JA Rocha, C Reis, F Simoes, J Fonseca… - Journal of …, 2005 - Springer
Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease.
ALS is a progressive neurodegenerative disorder, involving motor neurons in the cerebral …

Riluzole and amyotrophic lateral sclerosis survival: a population‐based study in southern Italy

S Zoccolella, E Beghi, G Palagano… - European journal of …, 2007 - Wiley Online Library
Riluzole is to date the only treatment that prolongs amyotrophic lateral sclerosis (ALS)
survival. However, results on the efficacy of riluzole in observational population‐based …

Introduction to supplement: The current status of treatment for ALS

RG Miller, SH Appel - Amyotrophic Lateral Sclerosis and …, 2017 - Taylor & Francis
ALS is a lethal neurodegenerative disease wherein the diagnosis is often delayed. Our
understanding of the pathobiology is slowly expanding, and the number of new genes is …