The lymphatic vasculature revisited

D Kerjaschki - The Journal of clinical investigation, 2014 - Am Soc Clin Investig
Lymphatic vessels constitute a ubiquitous countercurrent system to the blood vasculature
that returns interstitial fluid, salts, small molecules, resorbed fat, and cells to the bloodstream …

Lymphatic vasculature: a molecular perspective

B Hosking, T Makinen - Bioessays, 2007 - Wiley Online Library
The lymphatic vasculature comprises an intricate network of vessels critical for fluid
homeostasis, immune surveillance and fat absorption. Recent studies have provided …

[HTML][HTML] The lymphatic vasculature in the 21st century: novel functional roles in homeostasis and disease

G Oliver, J Kipnis, GJ Randolph, NL Harvey - Cell, 2020 - cell.com
Mammals have two specialized vascular circulatory systems: the blood vasculature and the
lymphatic vasculature. The lymphatic vasculature is a unidirectional conduit that returns …

The lymphatic vasculature: development and role in shaping immunity

KL Betterman, NL Harvey - Immunological Reviews, 2016 - Wiley Online Library
The lymphatic vasculature is an integral component of the immune system. Lymphatic
vessels are a key highway via which immune cells are trafficked, serving not simply as a …

Lymphatic vessels in health and disease

CT Kesler, S Liao, LL Munn… - … : Systems Biology and …, 2013 - Wiley Online Library
The lymphatic vasculature plays vital roles in tissue fluid balance, immune defense,
metabolism, and cancer metastasis. In adults, lymphatic vessel formation and remodeling …

Molecular biology and pathology of lymphangiogenesis

T Karpanen, K Alitalo - Annu. Rev. Pathol. Mech. Dis., 2008 - annualreviews.org
The lymphatic vasculature is essential for the maintenance of tissue fluid balance, immune
surveillance, and adsorption fatty acids in the gut. The lymphatic vessels are also crucially …

The lymphatic vasculature: An active and dynamic player in cancer progression

S Rezzola, EC Sigmund, C Halin… - Medicinal research …, 2022 - Wiley Online Library
The lymphatic vasculature has been widely described and explored for its key functions in
fluid homeostasis and in the organization and modulation of the immune response. Besides …

Lymphatic network in atherosclerosis: the underestimated path

A Milasan, J Ledoux, C Martel - Future science OA, 2015 - Taylor & Francis
The lymphatic system is a key component of tissue fluid homeostasis. In contrast to the
closed and high-pressure blood vascular system, the lymphatic vascular system transports …

The lymphatic system in health and disease

LN Cueni, M Detmar - Lymphatic research and biology, 2008 - liebertpub.com
The lymphatic vascular system has an important role in the regulation of tissue pressure,
immune surveillance and the absorption of dietary fat in the intestine. There is growing …

Molecular and metabolic orchestration of the lymphatic vasculature in physiology and pathology

N Montenegro-Navarro, C García-Báez… - Nature …, 2023 - nature.com
Lymphangiogenesis refers to the generation of new lymphatic vessels from pre-existing
ones. During development and particular adult states, lymphatic endothelial cells (LEC) …