Tumor necrosis factor (TNF) is a cytokine with well known anticancer properties and is being
utilized as anticancer agent for the treatment of patients with locally advanced solid tumors …

Tumor necrosis factor (TNF), a potent cytokine produced mainly by activated macrophages,
has numerous biological functions, including hemorrhagic necrosis of transplanted tumors …

In addition to the induction of tumor regression, tumor necrosis factor (TNF) has been
implicated as the causative agent in a number of pathologies, including cachexia, septic …

Abstract Tumor Necrosis Factor (TNF), released by induced macrophages, causes tumor
necrosis in animals, and preferentially kills transformed cells in vitro. Using pure …

Tumor necrosis factor (TNF) is a multifunctional cytokine which has excited and fascinated
numerous investigators and commercial entities due to its promise as a therapeutic agent …

Homeostasis at the cellular level appears to be a complex state of equilibrium derived, in
part, from multiple interactions among lymphokines, cytokines, growth factors, and …

Although tumor necrosis factor (TNF) initially came to prominence because of its anti-tumor
activity, most attention is now focused on its proinflammatory actions. TNF appears to play a …

Anti-tumour necrosis factor (TNF) antibodies have been widely used for approximately 25
years now. The first clinical observations in patients with refractory Crohn's disease rapidly …

Although TNF plays an important role in several physiological and pathological conditions,
the hallmark of this important cytokine has been its selective cytotoxic activity on tumor cells …