Time-of-flight secondary ion mass spectrometry (TOF-SIMS) has unique capabilities in the
area of high-resolution mass spectrometric imaging of biological samples. The technique …

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) provides a method for the
detection of native and exogenous compounds in biological samples on a cellular scale …

This concise tutorial review provides a description of the current state of the art in the
application of time-of flight based secondary ion mass spectrometry (TOF-SIMS) in the field …

Time‐of‐flight secondary ion mass spectrometry (ToFSIMS) is being applied increasingly to
the study of biological systems where the chemical specificity of mass spectrometry and the …

Time-of-flight secondary ion mass spectrometry (ToF–SIMS) imaging is an analytical
technique rapidly expanding in use in biological studies. This technique is based on high …

Secondary ion mass spectrometry (SIMS) is a technique capable of imaging tissues, single
cells, and microbes revealing chemical species with sub-micrometer spatial resolution. The …

Rationale In Time‐of‐Flight Secondary Ion Mass Spectrometry (TOF‐SIMS), pulsed and
focused primary ion beams enable mass spectrometry imaging, a method which is …

Fundamental advances in secondary ion mass spectrometry (SIMS) now allow for the
examination and characterization of lipids directly from biological materials. The successful …

In principle mass spectral imaging has enormous potential for discovery applications in
biology. The chemical specificity of mass spectrometry combined with spatial analysis …

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) using buckminsterfullerene
(C60) as the primary ion source has the ability to generate chemical images of surfaces with …