Renal cells from spermatogonial germline stem cells protect against kidney injury

L De Chiara, S Fagoonee, A Ranghino… - Journal of the …, 2014 - journals.lww.com
Spermatogonial stem cells reside in specific niches within seminiferous tubules and
continuously generate differentiating daughter cells for production of spermatozoa. Although …

Renal differentiation from adult spermatogonial stem cells

R Heer, AC Hepburn, SC Williamson, A Kennedy… - Renal failure, 2013 - Taylor & Francis
There is considerable interest in the use of multi-potent stem cells in kidney tissue
regeneration. We studied if spermatogonial stem cells have the ability to undergo kidney …

[HTML][HTML] Spermatogonial stem cells are a promising and pluripotent cell source for regenerative medicine

Z Chen, F Hong, Z Wang, D Hao… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Regenerative medicine has been shown to hold enormous potential to treat traumatic and
degenerative diseases, and substantial advancements have been made in the recent …

Conversion of adult mouse unipotent germline stem cells into pluripotent stem cells

K Ko, MJ Araúzo-Bravo, J Kim, M Stehling… - Nature protocols, 2010 - nature.com
Germline stem cells (GSCs), often called spermatogonial stem cells, are unipotent stem cells
that can give rise only to gametes. Under defined culture conditions, unipotent GSCs can be …

Characterization of human mesenchymal stem cells isolated from the testis

L De Chiara, ES Famulari, S Fagoonee… - Stem Cells …, 2018 - Wiley Online Library
Mesenchymal stem cells hold great promise for regenerative medicine as they can be easily
isolated from different sources such as adipose tissue, bone marrow, and umbilical cord …

[HTML][HTML] Stem cells derived from testis show promise for treating a wide variety of medical conditions

K Nayernia - Cell Research, 2007 - nature.com
The continuation of the spermatogenic process throughout life relies on a proper regulation
of self-renewal and differentiation of germline testis stem cells, the spermatogonial stem …

Spermatogonial stem cells: mouse and human comparisons

M Dym, M Kokkinaki, Z He - Birth Defects Research Part C …, 2009 - Wiley Online Library
Spermatogonial stem cells (SSCs) have unique characteristics in that they produce sperm
that transmit genetic information from generation to generation and they can be …

[HTML][HTML] In vitro derivation and propagation of spermatogonial stem cell activity from mouse pluripotent stem cells

Y Ishikura, Y Yabuta, H Ohta, K Hayashi, T Nakamura… - Cell reports, 2016 - cell.com
The in vitro derivation and propagation of spermatogonial stem cells (SSCs) from pluripotent
stem cells (PSCs) is a key goal in reproductive science. We show here that when …

Spermatogonial stem cells: A story of self-renewal and differentiation.

SK Subash, PG Kumar - Frontiers in bioscience (Landmark edition), 2021 - europepmc.org
Mammalian spermatogenesis is a complex but well-coordinated process in which
spermatogonial stem cells (SSC) of the testis develop to form spermatozoa. During testicular …

Identification of spermatogonial stem cell subsets by morphological analysis and prospective isolation

L Grisanti, I Falciatori, M Grasso, L Dovere, S Fera… - Stem …, 2009 - academic.oup.com
Spermatogenesis is maintained by a pool of spermatogonial stem cells (SSCs). Analyses of
the molecular profile of SSCs have revealed the existence of subsets, indicating that the …