The inflammatory response is of prime importance in liver disease, irrespective of inciting
cause, and is inextricably linked to oxidative stress and the generation of reactive oxygen …

Oxidative stress and liver injury are strongly associated. Oxidative stress in the liver can be
triggered during different conditions and by specific etiologies, including hepatotoxins …

Liver cell death induced by stresses such as ischemia‐reperfusion, cholestasis and drug
toxicity can trigger a sterile inflammatory response with activation of innate immune cells …

Reactive oxygen species (ROS) are important cytotoxic and signalling mediators in the
pathophysiology of inflammatory liver diseases. They can be generated by resident and …

In humans, oxidative stress and antioxidant defenses are the sum of a complicated network
of enzymatic and non‐enzymatic processes. Depending on the stage and severity of …

The role of oxidative stress in causing liver diseases emerged in the early 1960s from the
laboratories of Trevor Slater, Mario Umberto Dianzani and others. These pioneering works …

The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

The role of oxidative stress and related reactive intermediates has been discussed,
including reactive oxygen species, aldehydic end-products of lipid peroxidation such as 4 …

Oxygen is vital for life as it is required for many different enzymatic reactions involved in
intermediate metabolism and xenobiotic biotransformation. Moreover, oxygen consumption …

Liver fibrosis can be considered as a dynamic and highly integrated cellular response to
chronic liver injury [1]. Whatever the etiology, the evolution of chronic liver disease (CLD) is …