The S447X variant of lipoprotein lipase gene is inversely associated with severity of coronary artery disease

M Agirbasli, MC Sumerkan, F Eren, D Agirbasli - Heart and vessels, 2011 - Springer
Hyperlipidemia is a major risk factor for coronary artery disease (CAD). Lipoprotein lipase
(LPL) is an important enzyme in lipoprotein metabolism. S447X polymorphism of the LPL …

Functional significance of lipoprotein lipase HindIII polymorphism associated with the risk of coronary artery disease

Q Chen, H Razzaghi, FY Demirci, MI Kamboh - Atherosclerosis, 2008 - Elsevier
Lipoprotein lipase (LPL) plays a pivotal role in lipid metabolism by hydrolyzing triglyceride
(TG)-rich lipoprotein particles. Abnormalities in normal LPL function are associated with the …

Relationship between a novel polymorphism of lipoprotein lipase gene and coronary heart disease.

Z Su, S Zhang, Y Hou, L Zhang, L Liao… - Chinese medical …, 2002 - europepmc.org
Objective To investigate polymorphisms in the gene for lipoprotein lipase (LPL) in Chinese
populations with coronary heart disease (CHD) and to inquire into the relationship between …

Association of lipoprotein lipase gene polymorphisms with coronary artery disease

JL Anderson, GJ King, TL Bair, SP Elmer… - Journal of the American …, 1999 - jacc.org
OBJECTIVES The purpose of this study was to test whether the Hin dIII (+) and Pvu II (−) or
(+) restriction enzyme–defined alleles are associated with angiographic coronary artery …

[PDF][PDF] Analysis of the association Hind III Polymorphism of Lipoprotein Lipase gene on the risk of coronary artery disease

M Imeni, M Hasanzad, T Naji, B Poopak, M Babanejad… - 2013 - sid.ir
Abstract Background and Aim: Coronary artery disease (CAD) is one of the leading causes
of death and disability around the world. Interaction between genetic and environmental …

A common truncation variant of lipoprotein lipase (Ser447X) confers protection against coronary heart disease: the Framingham Offspring Study

SE Gagne, MG Larson, SN Pimstone… - Clinical …, 1999 - Wiley Online Library
Genetic variation at the lipoprotein lipase (LPL) locus has been shown to influence plasma
lipids and to modulate risk of coronary heart disease (CHD). Recently, we found that the …

Single-nucleotide polymorphisms in the lipoprotein lipase gene associated with coronary heart disease in Chinese

ZG Su, SZ Zhang, YP Hou, T Li, DW Nebert… - European Journal of …, 2002 - Elsevier
Coronary heart disease is a complex disease reflecting the interaction of multiple genes with
the environment (eg diet, life style). Lipoprotein lipase (LPL) plays an important role in lipid …

Lipoprotein lipase gene polymorphisms in Croatian patients with coronary artery disease

G Ferenčak, D Pašalić, B Grškovic, S Cheng, B Fijal… - 2003 - degruyter.com
Modifications in lipoprotein lipase levels lead to elevated triglycerides and reduced high
density lipoprotein (HDL), both of which are risk factors for coronary artery disease (CAD) …

Associations of three lipoprotein lipase gene polymorphisms, lipid profiles and coronary artery disease

MS Daoud, FS Ataya, D Fouad… - Biomedical …, 2013 - spandidos-publications.com
Lipoprotein lipase (LPL) plays a central role in lipoprotein metabolism by hydrolyzing the
core triglycerides (TGs) of circulating chylomicrons and very-low-density lipoprotein (VLDL) …

Potentially protective effects of the Ser447-Ter mutation of the lipoprotein lipase gene against the development of coronary artery disease in Japanese subjects via a …

M Sawano, Y Watanabe, H Ohmura… - Japanese circulation …, 2001 - jstage.jst.go.jp
Several DNA variants at the lipoprotein lipase (LPL) gene locus have been found to be
associated with the plasma lipid levels and the prevalence of coronary artery disease (CAD) …