Effects of isoflavones on behavior, estradiol, glutamate, and GABA levels in intact middle-aged female rats

TM Sandini, TM Reis-Silva, N Moreira… - Nutritional …, 2019 - Taylor & Francis
Objectives: Estrogen and phytoestrogens, mainly isoflavones (SIF) treatment has been
suggested to improve mood, behavior, and cognitive function in postmenopausal women …

Anti-anxiety, cognitive, and steroid biosynthetic effects of an isoflavone-based dietary supplement are gonad and sex-dependent in rats

J Friedman, C Frye - Brain research, 2011 - Elsevier
Isoflavone-rich diets are associated with reduced menopausal symptoms and lowered risk of
cancers of reproductive tissues. Isoflavones may mimic some effects of estrogen by binding …

The interaction of dietary isoflavones and estradiol replacement on behavior and brain-derived neurotrophic factor in the ovariectomized rat

AL Russell, JM Grimes, DO Larco, DF Cruthirds… - Neuroscience …, 2017 - Elsevier
Phytoestrogens are plant derived, non-steroidal compounds naturally found in rodent chows
that potentially have endocrine-disrupting effects. Isoflavones, the most common …

[PDF][PDF] The effects of soy milk and isoflavone supplements on cognitive performance in healthy, postmenopausal women

LR Fournier, TA Ryan-Borchers… - Journal of Nutrition …, 2007 - researchgate.net
Rationale: The decline in estrogen concentrations in women after menopause can
contribute to healthrelated changes including impairments in cognition, especially memory …

WHI and WHIMS follow-up and human studies of soy isoflavones on cognition

L Zhao, RD Brinton - Expert review of neurotherapeutics, 2007 - Taylor & Francis
Recent follow-up analyses of the previous findings from the Women's Health Initiative and
the Women's Health Initiative Memory Study confirmed some health benefits of estrogen …

[HTML][HTML] Psychological assessment of the effects of treatment with phytoestrogens on postmenopausal women: a randomized, double-blind, crossover, placebo …

ML Casini, G Marelli, E Papaleo, A Ferrari… - Fertility and sterility, 2006 - Elsevier
OBJECTIVE: To investigate the effects of soy isoflavones on mood and cognitive function in
postmenopausal women. DESIGN: Randomized, double-blind, cross-over, placebo …

Improved cognitive function in postmenopausal women after 12 weeks of consumption of a soya extract containing isoflavones

R Duffy, H Wiseman, SE File - Pharmacology Biochemistry and Behavior, 2003 - Elsevier
We previously reported that a high soya diet improved memory and frontal lobe function in
young volunteers, and since soya isoflavones are agonists at oestrogen receptors, they may …

Isoflavones and cognitive function in older women: the SOy and Postmenopausal Health In Aging (SOPHIA) Study

D Kritz-Silverstein, D Von Mühlen, E Barrett-Connor… - Menopause, 2003 - journals.lww.com
Objective This study examines the effects of a dietary supplement of isoflavones on cognitive
function in postmenopausal women. Design Participants for this 6-month, double-blind …

Dietary isoflavones alter regulatory behaviors, metabolic hormones and neuroendocrine function in Long-Evans male rats

ED Lephart, JP Porter, TD Lund, L Bu… - Nutrition & …, 2004 - Springer
Background Phytoestrogens derived from soy foods (or isoflavones) have received
prevalent usage due to their'health benefits' of decreasing: a) age-related diseases, b) …

17β-Estradiol and genistein acute treatments improve some cerebral cortex homeostasis aspects deteriorated by aging in female rats

J Morán, P Garrido, A Alonso, E Cabello… - Experimental …, 2013 - Elsevier
Aging is associated with decreased insulin sensitivity and impaired cerebral glucose
homeostasis. These changes increase neural sensitivity to metabolic damage contributing to …