Correlation of brain default mode network activation with bipolarity index in youth with mood disorders

KA Ford, J Théberge, RJ Neufeld… - Journal of affective …, 2013 - Elsevier
Abstract Background Major Depressive Disorder (MDD) and Bipolar Disorder (BD) can be
difficult to differentiate, as both feature depressive episodes. Here we have utilized fMRI and …

Aberrant resting-state functional connectivity in the default mode network in pediatric bipolar disorder patients with and without psychotic symptoms

Y Zhong, C Wang, W Gao, Q Xiao, D Lu, Q Jiao… - Neuroscience …, 2019 - Springer
Mood disorders/psychosis have been associated with dysfunctions in the default mode
network (DMN). However, the relative contributions of DMN regions to state and trait …

Differential brain network activity across mood states in bipolar disorder

RO Brady Jr, N Tandon, GA Masters, A Margolis… - Journal of affective …, 2017 - Elsevier
Background This study aimed to identify how the activity of large-scale brain networks differs
between mood states in bipolar disorder. The authors measured spontaneous brain activity …

The different impact of depressive or manic first-episode on pediatric bipolar disorder patients: evidence from resting-state fMRI

G Zhang, Q Xiao, C Wang, W Gao, L Su, G Lu, Y Zhong - Neuroscience, 2023 - Elsevier
Bipolar disorder may begin as depression or mania, which can affect the treatment and
prognosis of bipolar disorder. However, the physiological and pathological differences of …

Differentiating unipolar and bipolar depression by alterations in large‐scale brain networks

R Goya‐Maldonado, K Brodmann, M Keil… - Human brain …, 2016 - Wiley Online Library
Background Misdiagnosing bipolar depression can lead to very deleterious consequences
of mistreatment. Although depressive symptoms may be similarly expressed in unipolar and …

Differential failure to deactivate the default mode network in unipolar and bipolar depression

E Rodríguez‐Cano, S Alonso‐Lana, S Sarró… - Bipolar …, 2017 - Wiley Online Library
Objectives Neuroimaging studies have revealed evidence of brain functional abnormalities
in bipolar depressive disorder (BDD) and major depressive disorder (MDD). However, few …

Regional homogeneity within the default mode network in bipolar depression: a resting-state functional magnetic resonance imaging study

CH Liu, X Ma, F Li, YJ Wang, CL Tie, SF Li, TL Chen… - PloS one, 2012 - journals.plos.org
Aim We sought to use a regional homogeneity (ReHo) approach as an index in resting-state
functional magnetic resonance imaging (fMRI) to investigate the features of spontaneous …

Neural activity to intense positive versus negative stimuli can help differentiate bipolar disorder from unipolar major depressive disorder in depressed adolescents: a …

RS Diler, JRC de Almeida, C Ladouceur… - Psychiatry Research …, 2013 - Elsevier
Failure to distinguish bipolar depression (BDd) from the unipolar depression of major
depressive disorder (UDd) in adolescents has significant clinical consequences. We aimed …

Disrupted default mode network connectivity in bipolar disorder: a resting-state fMRI study

L Zhao, Q Bo, Z Zhang, F Li, Y Zhou, C Wang - BMC psychiatry, 2024 - Springer
Background Theoretical and empirical evidence indicates the critical role of the default
mode network (DMN) in the pathophysiology of the bipolar disorder (BD). This study aims to …

Neural correlates of treatment response in depressed bipolar adolescents during emotion processing

RS Diler, CD Ladouceur, AM Segreti… - Brain imaging and …, 2013 - Springer
Depressive mood in adolescents with bipolar disorder (BDd) is associated with significant
morbidity and mortality, but we have limited information about neural correlates of …