COPD is a complex mix of signs and symptoms in patients with chronic bronchitis and
emphysema, diseases that largely result from cigarette smoking. Not all smokers, however …

Chronic obstructive pulmonary disease (COPD) is a common and progressive disease that
is influenced by both genetic and environmental factors. For many years, knowledge of the …

Chronic obstructive pulmonary disease (COPD) is a significant cause of global morbidity
and mortality. Previous studies have shown that COPD aggregates in families, suggesting a …

Background There is notable heterogeneity in the clinical presentation of patients with
COPD. To characterise this heterogeneity, we sought to identify subgroups of smokers by …

Background: COPDGene is a multicenter observational study designed to identify genetic
factors associated with COPD. It will also characterize chest CT phenotypes in COPD …

Chronic obstructive pulmonary disease (COPD) affects over 10 million Americans. 1 This
complex disorder demonstrates many different presentations in a wide variety of patients …

The Genetic Epidemiology of COPD (COPDGene) study is a noninterventional, multicenter,
longitudinal analysis of> 10,000 subjects, including smokers with a≥ 10 pack-year history …

COPD is a highly prevalent disorder that results from the interplay of genetic susceptibility
and environmental exposures. Over the past 2 decades, significant technological advances …

Familial aggregation of chronic obstructive pulmonary disease (COPD) has been
demonstrated, suggesting that genetic factors likely influence the variable development of …

Chronic obstructive pulmonary disease (COPD) is a devastating clinical problem. In the
USA, it affects w16 million people, accounts for 13% of hospitalizations, and is the fourth …