Diterpenoid natural compound C4 (Crassin) exerts cytostatic effects on triple-negative breast cancer cells via a pathway involving reactive oxygen species

CE Richards, SH Vellanki, YE Smith, AM Hopkins - Cellular Oncology, 2018 - Springer
Purpose Triple-negative breast cancers (TNBC) lack expression of three common cell
surface receptors, ie, estrogen receptor (ER), progesterone receptor (PR) and human …

[HTML][HTML] Arnicolide d inhibits triple negative breast cancer cell proliferation by suppression of Akt/mTOR and STAT3 signaling pathways

Z Qu, Y Lin, DKW Mok, Q Bian, WCS Tai… - International Journal of …, 2020 - ncbi.nlm.nih.gov
Abstract Triple-Negative Breast Cancer (TNBC) is a most dangerous breast cancer subtype.
The naturally occurring sesquiterpene lactone, arnicolide D (AD), has proven effective …

Arachidin-1, a prenylated stilbenoid from peanut, induces apoptosis in triple-negative breast cancer cells

S Mohammadhosseinpour, LC Ho, L Fang… - International Journal of …, 2022 - mdpi.com
Triple-negative breast cancer (TNBC) is unresponsive to typical hormonal treatments,
causing it to be one of the deadliest forms of breast cancer. Investigating alternative …

Brevilin A, a natural sesquiterpene lactone inhibited the growth of triple-negative breast cancer cells via Akt/mTOR and STAT3 signaling pathways

Z Qu, Y Lin, DKW Mok, Q Bian, WCS Tai… - OncoTargets and …, 2020 - Taylor & Francis
Purpose Triple-negative breast cancer (TNBC) is aa breast cancer subtype characterized by
a lack of estrogen receptor, progesterone receptor and human epidermal growth receptor 2 …

[HTML][HTML] Phytoagent deoxyelephantopin derivative inhibits triple negative breast cancer cell activity by inducing oxidative stress-mediated paraptosis-like cell death

JY Shiau, K Nakagawa-Goto, KH Lee, LF Shyur - Oncotarget, 2017 - ncbi.nlm.nih.gov
Triple negative breast cancer (TNBC) is a highly metastatic cancer among the breast cancer
subgroups. A thorny issue for clinical therapy of TNBC is lack of an efficient targeted …

The potential of natural products in the treatment of triple-negative breast cancer

DYJ Ke, S El-Sahli, L Wang - Current cancer drug targets, 2022 - benthamdirect.com
Triple-negative breast cancer (TNBC) is a subtype of breast cancer that lacks receptors for
targeted therapy. Consequently, chemotherapy is currently the mainstay of systemic …

Antitumor Activity of Vanicoside B Isolated from Persicaria dissitiflora by Targeting CDK8 in Triple-Negative Breast Cancer Cells

D Kim, CY Wang, R Hu, JY Lee, TTT Luu… - Journal of natural …, 2019 - ACS Publications
A flavonoid glycoside, quercitrin (1), and two phenylpropanoyl sucrose derivatives,
vanicoside B (2) and lapathoside C (3), were isolated for the first time from the herb …

4-Acetylantroquinonol B induced DNA damage response signaling and apoptosis via suppressing CDK2/CDK4 expression in triple negative breast cancer cells

PB Satriyo, CM Su, JR Ong, WC Huang, IH Fong… - Toxicology and Applied …, 2021 - Elsevier
Background Triple-negative breast cancer (TNBC) has a more aggressive phenotype and
poorer prognosis than hormone receptor (HR+) and human epidermal growth factor receptor …

Sesquiterpenoids from Inula britannica and Their Potential Effects against Triple-Negative Breast Cancer Cells

RY Qi, C Guo, XN Peng, JJ Tang - Molecules, 2022 - mdpi.com
Flowers of Inula britannica commercially serve as pharmaceutical herbs in the
manufacturing of medicinal products. In the current study, sesquiterpenoids of I. britannica …

SH003 and Docetaxel Show Synergistic Anticancer Effects by Inhibiting EGFR Activation in Triple‐Negative Breast Cancer

YJ Choi, K Lee, JH Yoon, SG Cho… - BioMed Research …, 2022 - Wiley Online Library
Although many anticancer drugs have been developed for triple‐negative breast cancer
(TNBC) treatment, there are no obvious therapies. Moreover, the combination of epidermal …