Cellular senescence is a state of permanent cell cycle arrest activated in response to
different damaging stimuli. Activation of cellular senescence is a hallmark of various …

Cellular senescence refers to the irreversible growth arrest of normally dividing cells in
response to various types of stress. Cellular senescence is induced by telomere shortening …

In response to cellular stress or damage, proliferating cells can induce a specific program
that initiates a state of long-term cell-cycle arrest, termed cellular senescence. Accumulation …

Cellular senescence is the dynamic process of durable cell-cycle arrest. Senescent cells
remain metabolically active and often acquire a distinctive bioactive secretory phenotype …

Cellular senescence is a cell fate triggered in response to stress and is characterized by
stable cell-cycle arrest and a hypersecretory state. It has diverse biological roles, ranging …

Cellular senescence is a permanent state of cell cycle arrest that promotes tissue
remodeling during development and after injury, but can also contribute to the decline of the …

Cellular senescence, a permanent state of cell cycle arrest, is believed to have originally
evolved to limit the proliferation of old or damaged cells. However, it has been recently …

Cellular senescence is a permanent state of cell cycle arrest that occurs in proliferating cells
subjected to different stresses. Senescence is, therefore, a cellular defense mechanism that …

Replicative senescence, a process first described almost 40 years ago, entails irreversible
growth arrest with sustained metabolic functions, and it is also associated with increased …

Cellular senescence is a tumor‐suppressor mechanism that has been shown to occur in
response to multiple signals, including oncogenic stress, DNA damage, oxidative stress …