In vivo water state measurements in breast cancer using broadband diffuse optical spectroscopy

SH Chung, AE Cerussi, C Klifa, HM Baek… - Physics in Medicine …, 2008 - iopscience.iop.org
Structural changes in water molecules are related to physiological, anatomical and
pathological properties of tissues. Near infrared (NIR) optical absorption methods are …

Near infrared spectroscopy and imaging to probe differences in water content in normal and cancer human prostate tissues

JH Ali, WB Wang, M Zevallos… - Technology in cancer …, 2004 - journals.sagepub.com
The content of water in cancerous and normal human prostate in vitro tissues was shown to
be different using near infrared (NIR) spectroscopy. The water absorption peaks at 1444 nm …

In vivo absorption, scattering, and physiologic properties of 58 malignant breast tumors determined by broadband diffuse optical spectroscopy

A Cerussi, N Shah, D Hsiang, A Durkin… - … of biomedical optics, 2006 - spiedigitallibrary.org
Diffuse optical imaging (DOI) may be a beneficial diagnostic method for women with
mammographically dense breast tissue. In order to evaluate the utility of DOI, we are …

The cellular environment of cancerous human tissue. Interfacial and dangling water as a “hydration fingerprint”

H Abramczyk, B Brozek-Pluska, M Krzesniak… - … Acta Part A: Molecular …, 2014 - Elsevier
Despite a large number of publications, the role of water in the cellular environment of
biological tissue has not been clarified. Characterizing the biological interface is a key …

Non-invasive tissue temperature measurements based on quantitative diffuse optical spectroscopy (DOS) of water

SH Chung, AE Cerussi, SI Merritt, J Ruth… - Physics in Medicine & …, 2010 - iopscience.iop.org
We describe the development of a non-invasive method for quantitative tissue temperature
measurements using Broadband diffuse optical spectroscopy (DOS). Our approach is based …

Comparison of water and lipid content measurements using diffuse optical spectroscopy and MRI in emulsion phantoms

S Merritt, G Gulsen, G Chiou, Y Chu… - … in cancer research …, 2003 - journals.sagepub.com
We present a quantitative comparison of lipid and water signals obtained from broadband
Diffuse Optical Spectroscopy (DOS) and Magnetic Resonance Imaging (MRI). DOS and MRI …

Near-infrared tomography of breast cancer hemoglobin, water, lipid, and scattering using combined frequency domain and cw measurement

J Wang, BW Pogue, S Jiang, KD Paulsen - Optics letters, 2010 - opg.optica.org
In this study, near-IR tomography was implemented in the wavelength range from 661to948
nm to characterize breast tumors in vivo. Frequency-domain measurements provide …

Detecting human cancer through spectral optical imaging using key water absorption wavelengths

RR Alfano, JH Ali, W Wang, M Zevallos - US Patent 7,706,862, 2010 - Google Patents
Spectral optical imaging at one or more key water absorption fingerprint wavelengths
measures the difference in water content between a region of cancerous or precancerous …

[HTML][HTML] Collagen fibers mediate MRI-detected water diffusion and anisotropy in breast cancers

S Kakkad, J Zhang, A Akhbardeh, D Jacob… - Neoplasia, 2016 - Elsevier
Abstract Collagen 1 (Col1) fibers play an important role in tumor interstitial macromolecular
transport and cancer cell dissemination. Our goal was to understand the influence of Col1 …

Technology insight: water diffusion MRI—a potential new biomarker of response to cancer therapy

DM Patterson, AR Padhani, DJ Collins - Nature clinical practice …, 2008 - nature.com
Abstract Diffusion-weighted MRI (DW-MRI) is a functional imaging technique that displays
information about the extent and direction of random water motion in tissues. Water …